Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced hepatocarcinogenesis in mice.

Here you will find all the discussions from the time this group was hosted on YahooGroups and groups.io
You can browse through these topics and reply to them as needed.
It is not possible to start new topics in this forum. Please use the respective other forums most related to your topic.
Post Reply
dihuang2
Posts: 20
Joined: Wed Jul 09, 2003 10:00 pm

Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced hepatocarcinogenesis in mice.

Post by dihuang2 »

A colleague forwarded this to me and I thought to share with all on this site.
BMC Complement Altern Med. 2002 Apr 10;2(1):4. Related Articles, Links

Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced hepatocarcinogenesis in mice.

Biswas SJ, Khuda-Bukhsh AR.

Cytogenetics Laboratory, Department of Zoology, University of Kalyani, Kalyani-741 235, W.B. India.

BACKGROUND: Crude extracts of Chelidonium majus, and also purified compounds derived from crude extracts of this plant, have been reported to exhibit anti-viral, anti-inflammatory, anti-tumor and anti-microbial properties both in vitro and in vivo. Chelidonium is a homeopathic drug routinely used against various liver disorders including cancer in humans. Two potencies of Chelidonium (Ch-30, Ch-200) have been tested for their possible anti-tumor and enzyme modulating activities in liver and anti-clastogenic effects during p-DAB-induced hepatocarcinogenesis in mice compared to suitable controls. METHODS: Several cytogenetic and enzymatic protocols were used at three fixation intervals; at 60 days, 90 days and 120 days of treatment. Different sets of healthy mice were fed: i) hepatocarcinogen, p-DAB plus phenobarbital (PB), ii) only PB, iii) neither p-DAB nor PB (normal control). One set of mice fed with p-DAB plus PB was also fed Ch-30 (iv) and another set Ch-200 (v). All standard
currently used methods were adopted for cytogenetical preparations and for the enzyme assays. RESULTS: All group (i) mice developed tumors in liver at all fixation intervals, while none of group (ii) and (iii) mice developed any tumors. About 40% mice in group (iv) and group (v) did not show tumor nodules in their liver. Feeding of Chelidonium to group (iv) and (v) mice reduced genotoxic effects to a significant extent (p < 0.05 to p < 0.001). CONCLUSION: The homeopathic drug Chelidonium exhibited anti-tumor and anti-genotoxic activities and also favorably modulated activities of some marker enzymes. Microdoses of Chelidonium may be effectively used in combating liver cancer.
---------------------------------
Do you Yahoo!?
Yahoo! Finance: Get your refund fast by filing online

[Non-text portions of this message have been removed]


Dale Moss
Posts: 1544
Joined: Wed Jul 31, 2002 10:00 pm

Re: Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced hepatocarcinogenesis in mice.

Post by Dale Moss »

Cool! It works in cats, too ;-)

Cinnabar


Post Reply

Return to “Minutus YahooGroup Archives”