Mad Cow lies, was Eggs-LESS, Going Vegan

[Sheri Nakken]

So many lies and misconceptions about Mad Cow - it was organo-phosphate poisoning for the cows and the humans, but the gov't forced the UK farmers to paint the spines of their cows with organophosphates. So they couldn't be blamed - blamed it on prions and anything else. Mark Purdy is who told the truth (someone I knew from England and my time living over there)
http://www.ourcivilisation.com/madcow/madcow.htm

http://www.cqs.com/opmadcow.htm

https://web.archive.org/web/20140711001 ... ode=PURDEY
"More sinister is the attention Purdey, and those who have taken up his theory, has received. His house mysteriously burnt down, and a barn collapsed onto his science library. He's been shot at, and following the publication of a 1993 Independent article, he awoke to find his telephone lines cut - preventing him receiving follow up media calls. Strangers, with in depth knowledge of his movements appear on his farm, freak his wife out and tail him when he travels. The solicitor who defended Purdey's High Court action died when his car went inexplicably out of control. Purdey's vet (who said this theory should be taken seriously) was killed in what the local rag described as: 'Mystery vet death riddle,' when his car was 'magnetised' into the front of an oncoming lorry on a clear straight road. "

Mark died of a brain tumour in 2006.

google mad cow disease organophosphates mark purdey for more
Sheri
Sheri Nakken, former R.N., MA, Hahnemannian Homeopath
http://homeopathycures.wordpress.com/ & http://vaccinationdangers.wordpress.com/
ONLINE/Email classes in Homeopathy; Vaccine Dangers; Childhood Diseases and Child Health
Next classes start in October

[Tanya Marquette]

Interesting. I seem to remember something about toxicity in the soil or some significant deficiency that
was a cause of Mad Cow.

OTH, I also thought the if feeding same species meat could cause such neurodegenerative conditions, how does this
relate to vaccines that use human fetal tissue for cultures?

t

[Irene de Villiers]

No thanks.
Your wild story against the existence of prions is as off the wall as your lack of knowledge about other microbes.

Prion diseases - lots of them - have been around since 1730. Mad cow is the most recetn one. Man's usual stupidity triggered it.

Mammals all have normal "cellular prion protein" (CPP). Proteins have a large and complex molecular shape, with lots of atoms in a single molecule, hundreds in some cases. But this one can get "folded" the wrong way. If one normal CPP becomes misfolded, (called SCPP) it becomes able to cause misfolding of other CPPs by aligning with them in a way that induces the misfolding. (Atoms all have positive and negative charges which can atract or repel), and in the case of cellular prion protein, its odd shape is such that it can become inappropriately "folded" - misfolding of the cellular prion protein into the kind that causes havoc in nerve tissue.
If you get a lot of misfolded prion protein it causes holes in the brain, with consequent nasty symptoms.

There are many diseases caused by cellular misfolded prion protein. Most are named for the species in which they tend to occur, for example scrapie in sheep, feline spongiform encelphalopathy in cats (as it turns the brain full of holes into something looking like a sponge) mad cow or bovine spongiform encephalopathy, etc for antelopes, goats, mink etc, and many more named for the person who discovered them or some other reason, such as kuru, Creutzfeld Jacob Disease, Gerstmann-Sträussler-Disease and the list goes on.
There is research showing where the folding of the cellupar prion protein took place, and it goes way back.
It's a bit technical (in italics so you can skip if you wish) but not too much to follow with a little genetics biology:
The prion protein founder gene was based on two genomic rearrangements that occurred hundreds of millions of years ago. The first event occurred within the N-terminal ectodomain of a ZIP predecessor gene, (A ZIP gene is involved in separating/rejoining DNA for replication) when metazoans first emerged on the planet. (Metazoans are multicellular animals that use mitochondrial energy - as we do - energy is made in tiny structures inside all cells called mitochondria - mitochondria also have geneteic material, it is not just cromosomes that have genes).
As a consequence of this rearrangement a cysteine-flanked core region (in the genes) was generated within this ectodomain. The second event, which allowed the creation of the prion protein founder gene to be traced back, occurred approximately a half-billion years ago (around the Cambrian explosion). This later event resulted in the apparent genomic retro-insertion of a spliced and C-terminally truncated ZIP gene transcript.
(So the prion is a bit like a retrogene.)

From there it gets complicated as the protein founder gene - the origin of the prion - can interact chemcially with several body chemical componenets, and in different ways and in different frequencies in different species or races.
In addition various other normal cellular prion protein mutations an individual may have or inherit, make it more or less likely that they can be affected by misfolded prion protein. For example codon 129 of the human cellular prion protein may mutate in a way to make Creutzfeld Jacob a higher susceptiility issue.

So prions are just isoforms of the normal cellular prion protein. An isoform is a molecule with the same atoms, but arranged in a different physical configuration....it's joining bonds between atoms are at different angles.
So essentially a prion is a specific squished protein (in need of ironing?), which tends to crumple other proteins to look like its shape, leaving holes where several folded proteins occur, so that brain tissue looks more like a sponge than a convoluted grey matter thing.

It has nothing to do with organophosphates of course.

Namaste,
Irene

--
Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom/D.Vet.Hom.
P.O. Box 4703 Spokane WA 99220.
www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)
"Man who say it cannot be done should not interrupt one doing it."

[Shannon Nelson]

Very interesting!

But doesn't it seem very plausible that strong changes in the chemical environment (e.g. toxic mineral excess and/or deficiency) could affect both the folding of one, and the susceptibility to re-folding of the other?

[Shannon Nelson]

Does the normal cellular prion protein pay a biological role specific to it, or is it just a usually benign variant?

[Tanya Marquette]

i don’t see a contradiction btw irene’s description of the condition as it manifests and Sheri’s claim that organophosphates are
a causative agent that make this aberration occur.

Tthere certainly are other toxicities which affect the brain and nervous system adversely. We know this to be true
with aluminum and mercury, to name only 2, elements with the capability to destroy brain tissue.

This fight here seems silly as it is 2 arguments on different levels.

t

[Irene de Villiers]

Prion proteins occur in most if not all species in the normal non-pathogenic form, but it is not clear if they do anything specific or if so what, normally.
They have been puzzling to research as they keep cropping up somewhere else they had not been looked for before, and there are many slightly different versions or strains of them. (Some fold types only occur in lab conditions during research.)
Also we do not fully know what makes them mis-fold except that it happens during new recruitment of polypeptide chains oin the are where ther is a cellular prion protein.
But we do know that once one has misfolded, it can have a domino effect to misfold others that it comes in contact with. And also - some of them replicate and fold wihtout causing illness.
All those that fold have something in common to do with where the folding starts - and to do with presence of new polypeptide chains.
Different prions fold different ways, and we do not know why. Some are pathogenic for sponge brain, some not.
So research is happening but the whole story is not known yet about what makes these things tick.
......Irene
--
Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom/D.Vet.Hom.
P.O. Box 4703 Spokane WA 99220.
www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)
"Man who say it cannot be done should not interrupt one doing it."

[Irene de Villiers]

Not the mechanism itself as it is specific, but I would expect toxins to make an individual more susceptible to prion folding possibility or prion entry into the system without being zapped by the immune system (as with any other chronic illness) or less able to fight it off with thymus activity or some such indirect but relevant effect.

Irene
--
..Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom/D.Vet.Hom.
P.O. Box 4703 Spokane WA 99220.
www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)
"Man who say it cannot be done should not interrupt one doing it."

[Sheri Nakken]

I also have many personal stories of farmers watching their cows go crazy after painting their spines with organophosphates (for warble fly) and also farmers who became ill after doing that too. I lived in Wales for 8 years in the UK. I personally knew Mark Purdey before he died.

Somehow you think, Irene, that you are a 'scientist' and know all. You are not and don't. Some may fall for all your wordiness here...............not I.

Sheri

At 05:35 AM 11/3/2014, you wrote:
Sheri Nakken, former R.N., MA, Hahnemannian Homeopath
http://homeopathycures.wordpress.com/ & http://vaccinationdangers.wordpress.com/
ONLINE/Email classes in Homeopathy; Vaccine Dangers; Childhood Diseases and Child Health
Next classes start in October