New Evidence (gene mutations) Antidepressants (and other drugs) Can Send You into a Murderous Rage (& more)

[Sheri Nakken]

Serious new information on the dangers for some with gene mutations (I would say dangers for all, but especially for those with gene mutations) (dangers of many different drugs including opiates, antidepressants, ibuprofen, amitryptline, benzos & more).............do you know people on some of these meds who have had serious bouts of rage, lost time, black outs, paranoia, and more.

"[The enzyme] CYP2D6 (cytochrome P450 2D6) acts on one-fourth of all prescription drugs, including the selective serotonin reuptake inhibitors (SSRI), tricyclic antidepressants (TCA), beta blockers, opiates, neuroleptics, antiarrhythmics and a variety of toxic plant substances.

Up to 15 percent of the population has a slow acting form of this enzyme and many of these a fast acting form.

35% are carriers of a non-functional CYP2D6 allele, especially elevating the risk of adverse drug reactions when these individuals are taking multiple drugs ...

This means that potentially up to 1 billion people on the planet cannot metabolize and eliminate the commonly prescribed drugs from their bodies".

http://articles.mercola.com/sites/artic ... artTest_C1

EXCERPTS from................

New Evidence Antidepressants Can Send You into a Murderous Rage
Posted By Dr. Mercola |

Story at-a-glance
"Homicidal akathisia" is an extreme motor restlessness sometimes caused by antidepressant and antipsychotic drugs that is thought to underlie these violent outbursts .............
By Dr. Mercola

More than a decade ago, Dr. Yolande Lucire started noticing high rates of hospital admission and suicide among patients treated with antidepressant medications and antipsychotics.

Since then, she has gathered evidence that makes it clear that many people being treated with antidepressants can't metabolize them due to common genetic mutations.

Dr. Lucire has been campaigning to introduce ways of minimizing over-prescription of antidepressants.

According to Prevent Disease:

"[The enzyme] CYP2D6 (cytochrome P450 2D6) acts on one-fourth of all prescription drugs, including the selective serotonin reuptake inhibitors (SSRI), tricyclic antidepressants (TCA), beta blockers, opiates, neuroleptics, antiarrhythmics and a variety of toxic plant substances.

Up to 15 percent of the population has a slow acting form of this enzyme and many of these a fast acting form.

Thirty-five percent are carriers of a non-functional CYP2D6 allele, especially elevating the risk of adverse drug reactions when these individuals are taking multiple drugs ...

This means that potentially up to 1 billion people on the planet cannot metabolize and eliminate the commonly prescribed drugs from their bodies".
From Depressed to Homicidal: The "Miracles" of Modern Pharmacy

Forensic psychiatrist Dr. Yolande Lucire and pharmacogeneticist Christopher Crotty found a significant association between genetics, metabolism of psychiatric drugs, and severe "homicidal akathisia."

Akathisia is a medical term describing a condition of motor restlessness, marked by anxiety, agitation, jitteriness, or the sensation of "jumping out of one's skin" and the inability to sit quietly or sleep. Akathisia is a common side effect of neuroleptic drugs. Chronic sleeplessness itself can lead to a long list of physical and emotional symptoms.

It has long been known that many antidepressants cause akathisia, especially SSRIs (selective serotonin reuptake inhibitors), a category that includes Prozac, Paxil, Zoloft, and other commonly prescribed antidepressants.

Some researchers and physicians believe that akathisia is the chief symptom that triggers impulsive violence in certain individuals who take antidepressant drugs.This is thought to be an extreme form of akathisia. Homicidal impulses and murderous behavior due to akathisia is now being called "homicidal akathisia."

The akathisia issue first came into public view shortly after Prozac entered the marketplace in the mid-1980s, when reports of murder and suicide among patients taking Prozac were publicized by the media. Since then, there have been thousands of reports of violent behavior by individuals taking antidepressant drugs. There is even a website devoted to collecting and indexing these reports in a sortable database. The site lists more than 4,800 cases, from murder-suicides to road rage to school shootings.........................

Lucire's CYP450 Gene Study

In the featured study , 138 people were tested for CYP450 genes; a family of genes thought to have metabolic consequences that lead to serotonin toxicity and resultant severe akathisia in some individuals.

Researchers examined 129 subjects who experienced drug-induced adverse events (mainly akathisia). Of the 129, 12 suffered disastrous consequences while taking antidepressant drugs:
1 sleepwalked to her death

So, these individuals sought help for ordinary emotional distress related to various life stressors, such as bereavement, marital difficulties, and work-related stressand the treatment resulted in homicide, suicide and unintentional death.

How can antidepressants that aim to improve your mood have such tragic and unintended consequences?

A certain family of genes, called CYP450 genes, cause metabolic processes in some people that lead to serotonin toxicity and severe akathisia.

These genes were found to be more prevalent among patients reporting akathisia than in the general public. What this means is, if you have these genes and you take antidepressants or a number of other drugs, you can develop serotonin toxicity and uncontrollable violent impulses.(For a complete list of CYP450 interactions, refer to this table on the Indiana University School of Medicine website.)

Patients experienced complete resolution of their akathisia when their antidepressant drugs were discontinued. Of course, it was too late for the four patients who had already killed themselves, and no way to bring back to life those killed by the other eight.

The authors concluded:

"The results presented here concerning a sample of persons given antidepressants for psychosocial distress demonstrate the extent to which the psychopharmacology industry has expanded its influence beyond its ability to cure."

But this isn't the only study that has shown these drugs to be extremely risky. The following are two more very recent studies that should give you serious pause before filling your prescription for a mind-altering medication.

Antidepressants Increase the Risk of Death Among the Elderly

In a study published in the British Medical Journal (BMJ) in August 2011, more than 60,000 adults over age 65 diagnosed with depression were tracked between 1996 and 2007. The findings are disturbing. Antidepressants were linked with higher risk of death from heart attack, stroke, falls, and seizures.

Additionally:
Seniors taking older (prior to SSRI) antidepressants showed an 8.1 percent risk of death.
Seniors taking SSRIs (the newer antidepressants) showed a 10.6 percent risk of death.

Have PTSD? Antidepressant and Antipsychotic Drugs are a Waste of Time and Money

A very large study of veterans with Post Traumatic Stress Disorder (PTSD), published in JAMA in 2011, showed that antipsychotic agents are no better than placebo at reducing the symptoms of PTSD. Government data shows that 10 to 20 percent of soldiers who see live combat develop PTSD. Of these, about one fifth are prescribed an antipsychotic drug, such as risperidone (Risperdal), after antidepressant treatment fails.

The lead author of the study, Dr. John Krystal, stated they could find NO benefit of antipsychotic drug treatment for the soldiers. Although this study involved only one antipsychotic medication (risperidone), the findings can be extrapolated to the entire class of drugs, including Seroquel, Geodon and Abilify.

This is such a typical approach of our healthcare systema hit and miss strategy, juggling mixtures and doses of different drugs in a ramshackle attempt to find something that works. Antidepressants aren't working, so they try you on antipsychotics, which turn out to be just as worthless. Meanwhile, your condition gets worse so you are given numerous other drugs to manage your ever-growing list of side effects.

Senior scientist Dr. Charles Hoge at Walter Reed Army Institute of Research commented on the PTSD study's findings:

"I think it's a very important study, given how frequently the drugs have been prescribed. It definitely calls into question the use of antipsychotics in general for PTSD."
http://vaccineliberationarmy.com/pharma ... psychotic/
Pharmagedon: Big Coverup: What is 2D6? Making our kids & soldiers psychotic!

First 39-45 vaccine doses by the time you are 6 years old. And now add the recent in-utero shot to the fetus-the flu shot with mercury. The epidemic of ADHD, ADD, OCD, Bipolar, Autism, encephalitis, narcolepsy is caused by the inordinate amount of vaccinations that are forced on children by our government in order to get into school. To compensate or mitigate the effects of the vaccine injury, mis-nomered as "mental illness" psyche drugs are given out like candy. 25 % of all American children are on psyche drugs.

And now the National Coalition of Organized Women uncover one of the most egregious Pharma sins in modern psyche history. The information that would have averted the school shootings, the homicides, the overdoses, the bizarre epidemic of mentally ill in recent years has been available for circa 15 years since gene mapping. Cytochrome P450 2D6 is the most major metabolic pathway that detoxifies 50% of all psyche drugs and street drugs. 7-10% of Caucasians, for example, are poor or non-metabolizers due to a deletion or non activity of the 2D6 pathway. There is a percentage of Asians and Afrikan Americans who are poor metabolizers. When certain drugs (list below) are given to these demographics, due to their inability to metabolize them, these people become psychotic, homicidal, suicidal, a danger to themselves and society. There are other pathways on Cytochrome P459 such as Cyt 3A4 implicated in the psychosis reports of soldiers on Larium, a malaria drug. Another example: Marijuana (Cannibals) is a powerful inhibitor of cytochrome P450 isozymes 3A4, 2C19, and 2D6.

Links below:

You know those kids who are shooting each other and mothers who drown their kids in the bath tub? Check out this most egregious cover up in the history of modern psychiatry. Dr. Lucire elucidates. Her study just published in the summer of 2011 is not only a academic victory but the homicidal speak of their experiences in their own words on how they were moved to kill their loved ones.

This information, now highlighted by Dr. Lucire has been heretofore suppressed by the stakeholder. The justice system in the USA has not realized the implication in law. (See personalized Justice/Personalize Medicine). These drugs force the patient who is a poor or non-metabolizer into heinous acts against themselves and society. And who and what is really complicit when a crime is committed? The manufacturer who "failed to warn"?; the physician who "failed to warn" and who did not do the simple genetic test? Read Dr. Lucire's study. She removed her subjects from the drugs and they regained their normal mental function. It was the drugs.now we have a legal test to prove it!

Dr. Yolande Lucire's recently published study

list of the drugs that need 2D6 pathway to metabolize

Laymen's Synopis

Mayo Clinic Report on 2D6

Psychosis reports of soldiers on Malaria Drugs

Comprehensive Article by Brandon Turberville

Dr. Mercola on Cytochrome P450 2D6

Personalized Justice/Personalize Medicine

Do you want the simple 2D6 gene test? Contact us at NCOWmail@gmail.com
http://www.dovepress.com/articles.php?article_id=7993
Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family
AT the end of the article click on Download Article for FULL study

http://vaccineliberationarmy.com/wp-con ... le-PDF.pdf
list of the drugs that need 2D6 pathway to metabolize

http://vaccineliberationarmy.com/wp-con ... -cyp-2.pdf

maybe this is what explains alcoholism too?
Sheri Nakken, former R.N., MA, Hahnemannian Homeopath
http://homeopathycures.wordpress.com/ & http://vaccinationdangers.wordpress.com/
ONLINE/Email classes in Homeopathy; Vaccine Dangers; Childhood Diseases
Next classes start May 18 & 25