Mitochondrial disease [was: Can I give Ignatia Amara 200K at the same time with Amylium Nitrosis 200K ?

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Shannon Nelson
Posts: 8848
Joined: Fri Jun 28, 2002 10:00 pm

Mitochondrial disease [was: Can I give Ignatia Amara 200K at the same time with Amylium Nitrosis 200K ?

Post by Shannon Nelson »

Hi Jacqueline,

While I have heard the phrase mitochondrial disorder (and I do know what mitochondria area), I don't know where the term came from, or just what it is describing. Mitochondria are the cells' energy centers; they produce the cellular energy. So if they are (as a group) under-functioning, the effects would affect I guess all of the body systems--but can you tell me just what leads to the diagnosis? What you and the vet observed, that led to that conclusion? (And without knjowledge of that term, how would you have described what was wrong, and what might she have diagnosed instead?) Mostly I am just curious...

Thanks,
Shannon


Sheltiekriebels
Posts: 17
Joined: Wed Apr 08, 2020 8:38 pm

Re: Mitochondrial disease [was: Can I give Ignatia Amara 200K at the same time with Amylium Nitrosis 200K ?

Post by Sheltiekriebels »

Hi Shannon,
A mitochondrial Encephalopathy is a desease that affects the organs who needs the most of oxigine. With the encephalopathy the nerves and the brain is affected by the desease.
You have also the Mitochondrial Myelopathy, that affects the nerves and the Muscles, or the Ecnemyolopathy that affects the muscles, nerves and brain. These are all progressive disorders. It can be triggerd by change or greef (in human) The mitochondria are damaged, and the more mitochondria are damaged the worse the desease is.

They test the urine on accids, the test is an urine Accid screentest, and they look if there are too many or no accids are in the urine. The urine Accid screentest showed by the first of my diagnosed dog, 11 of the 18 accids that were way to high. She was the first discoverd dog in the netherlands with this desease. It was tested in an human lab for mitochondrial disorders, there are only a few labatoria on the world who can test this.

What we first observed, was a puppy with moaning a lot, as if she was very tired (now we know it are headaches that cause Seizures (from 5 till 30 minutes or longer) or strokes (by lack of energy)
When she was 2 years old she did get her first seizure, during seizures she is somethimes awake and allert, but she can't do anything, because the seizure conrolles her body. After seizures she can only lay down, muscles don't work, she can't stand up, walk or sit. Somethimes she looks like a parkinsonpatient (seizures are look like that) But she also have generelised seizures. Muscle pain, Muscle weakness, movement intetollerance, tired, panting, coughing, throat tightness, sad eyes, wobbly on the legs, tired, heartproblems come when they are aging, low and unregular heartrate during warm weather, and normal and unreagular heartrate during cold weather, blue tongue (during lack of oxigine), neuropatic pain, problems with regulate temperature (temperature changing fast from stone cold to overheating) they are also full of fear when they have no good treatment. Somethimes they run away for nothing, flybiting is also a symptom, seeing things that not there, hiding for things that not there, one girl is always flybiting (without the flys) but when she is seeing a fly she runs away and hide.

With this girl we have most symptoms under control now, with vitamins (high dosages) Dog from 10 kg, does get megavites for human, high dosages of Amino accids, high dosages of Q10, heartmeds, No AED's that makes this illness more progressive.

Jacqueline
Hi Jacqueline,
While I have heard the phrase mitochondrial disorder (and I do know what mitochondria area), I don't know where the term came from, or just what it is describing. Mitochondria are the cells' energy centers; they produce the cellular energy. So if they are (as a group) under-functioning, the effects would affect I guess all of the body systems--but can you tell me just what leads to the diagnosis? What you and the vet observed, that led to that conclusion? (And without knjowledge of that term, how would you have described what was wrong, and what might she have diagnosed instead?) Mostly I am just curious...
Thanks,
Shannon


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