Rubella Vaccine Reactions

[Sheri Nakken]

Rubella Vaccine Reactions

http://chetday.com/novacarticles.html
RUBELLA VACCINE
Is RA27/3 Rubella immunization a cause of chronic fatigue (MEDICAL
HYPOTHESES 1988 27 pgs. 217-220) [4pgs]
Abstract- Patients with chronic fatigue syndrome (primary fibrositis
syndrome, major affective disorder ,etc.) have elevated IgG serum
antibodies to multiple common viruses. Only IgGrubella antibodies are
positively correlated with the intensity of symptoms and have a height that
is clearly significant compared to healthy controls. The lymphotrophic
properties of the rubella virus could account for the multiple elevated
antibodies. Adult women are over-represented in the population of patients
with chronic fatigue, and are especially susceptible to developing such
symptoms following exposure to attenuated rubella new more potent strain of
live rubella vaccine strain RA27/3 (my.02 this vaccine is the one using the
aborted fetal tissue cells) was introduced in 1979. Within three years,
reports of patients with chronic fatigue began surfacing in the literature.
Considering all this, the possible role of rubella immunizations in the
etiology of chronic fatigue syndrome deserves further study.

Rubella Vaccination of Hospital Employees (this talks about low
immunization rate in doctors) JAMA Feb.20,1981 Vol 245 No 7 [2pgs]

Two Syndromes Following Rubella Immunization (Suggests a polyneuropathy in
both syndromes) (JAMA 1970 Vol 214 no 13) [5pgs.]
Chronic Arthritis After Rubella Vaccination Clinical Infec Dis. 1992
15;307-12 [6pgs]
Acute Arthritis Complicating Rubella Vaccination (ARTHRITIS AND RHEUMATISM
1971 41) [4pgs]
Joint Symptoms Following an Area Wide Rubella Immunization Campaign Report
of a Survey Am J of Public Health Vol 62 no 5 [4pgs]
Polyneuropathy Following Rubella Immunization Am J Dis Child 1974 Vol 127
[5pgs]
Postpartum Rubella Immunization: Association with Development of Prolonged
Arthritis, Neurological Sequelae, and Chronic Rubella Viremia (THE JOURNAL
OF INFECTIOUS DISEASES 1985 vol 152 no 3) [7pgs]
Gamma Globulin Prophylaxis; Inactivated Rubella Virus; Production and
Biologics Control of Live Attenuated Rubella Virus Vaccines (this is
contains info on the use of human aborted fetal tissue cells in rubella
vaccine) Amer J Dis Child 1969 vol 118 [10 pgs] I am just going to point
out a few things in this article. The first part deals with gamma globulin.
The part of interest is the end where there is a discussion between doctors
and researchers, one being the famous Dr. Sabin. They begin discussing the
possible dangers of the aborted fetal tissue cells (they also discuss
animal use and its dangers) with possible genetic material passed over into
the vaccine. Also human leukemia viruses. They start discussing the aborted
fetus used in the WI-38 cell (this is the fetus tissue cells they use to
grow the disease on it is lung cells [diploid]). I am going to type part of
this discussion.
Dr. K McCarthy: It seems to me that there are two things that we worry
about in regards to WI-38 cell substrate. First of all, presence of
extraneous viral agents; secondly, the possibility of there being human
genetic material passed over into the vaccine. I wonder if there is any
information about the reasons for aborting that particular embryo that gave
rise to WI-38; and if it was from a family, whether we have any information
about siblings from the family and whether they are normal?
Dr. S Plotkin, Philidelphia: I should like to answer Dr. McCarthy's
question. This fetus was chosen by Dr. Sven Gard, specifically for this
purpose. Both parents are known, and unfortunately for the story, they are
married to each other, still alive and well, and living in Stockholm,
presumably. The abortion was done because they felt they had too many
children. There were no familial diseases in the history of either parent,
and no history of cancer specifically in the families; I believe this
answers Dr. McCarthy's question.
Dr Sabin goes on to say that this issue (objections to their use) is based
on emotion rather than reason. He then goes on talk about how in theory
something may show up later that we do not have the technology now to
discover (my .02 we all know they did not discover SV40 right away). Also
he talks about a number of researchers and the national Cancer Institute
are developing a program to determine whether the leukemia sarcoma complex
that has been now been so well characterized in avian species and in mice
may also have its counter part in human beings. (The discussion goes into
further detail.)
Production and Testing of Rubella Virus Vaccine (more on the use of aborted
fetal tissue cells) Amer J Dis Child 1969 Vol 118 pg. 367 [5 pgs]
The in vitro growth of rubella virus in human embryo cells (more on aborted
fetal tissue) Am J of Epidemiology Vol 81 no 1 [7pgs]
Studies of Immunization With Living Rubella Virus (more on aborted fetal
tissue) Amer J Dis Child vol 110 Oct 1965 [7pgs] This fetus was from a 25
year old mother exposed to rubella 8 days after last menstrual period.
Sixteen days later she developed rubella. The fetus was surgically aborted
17 days after maternal illness and dissected immediately. Explants from
several organs were cultured and successful cell growth was achieved from
lung, skin, and kidney. It was then grown on WI-38. This new vaccine was
tested on orphans in Philadelphia.
Attenuation of RA 27/3 Rubella virus in WI-38 Human Diploid Cells (more on
use of aborted fetal tissue) Amer J Dis Child Vol 118 1969 [7 pgs] Explant
cultures were made of the dissected organs of a particular fetus aborted
because of rubella, the 27th in our series of fetuses aborted during the
1964 epidemic. The third explant, which happened to be from kidney, was
selected arbitrarily for further study.
Serological Evidence of Reinfection among Vaccinees During Rubella Outbreak
Lancet Vol 336 pg. 1071 [1pg]
ing Vaccination With Attenuated Measles Virus Amer J Dis Child Jan 1968 Vol
115 [3pgs]
Most of these links don’t work any longer
I’ve corrected some of them on my webpage

http://www.nccn.net/~wwithin/rubella.htm

Also you can google on each title to get the correct URL – due to my
computer problems at the moment can’t do it for you

http://www.geocities.com/alebencal/Rubella.htm
links from the webpage
Rubella
Adverse effects
Retinal vasculitis caused by rubella.
Chronic arthropathy and musculoskeletal symptoms associated with rubella
vaccines
Peripheral neuropathy associated with anti-myelin basic protein antibodies
in a woman vaccinated with rubella virus vaccine.
Postpartum rubella immunization: association with development of prolonged
arthritis, neurological sequelae,
Randomised double-blind placebo-controlled study on adverse effects of
rubella immunisation in seronegative women.
Chronic rubella vaccine-associated arthropathy.
Is RA27/3 rubella immunization a cause of chronic fatigue?
Effect of immunization against rubella on lactation products
Epidemiology
Epidemiology of congenital rubella syndrome. The role of maternal parity.
The incidence of rubella virus infections in Switzerland after the
introduction of the MMR mass vaccination programme.
Susceptibility to rubella in a pregnant population after the introduction
of vaccination.
Rubella among the Amish:
Rubella immunity and morbidity: effects of vaccination in Finland
Reasons for rubella susceptibility among pregnant women in west Lambeth.
Antibodies and Immunity
Congenital rubella affecting an infant whose mother had rubella antibodies
before conception.
Rubella-specific immune complexes after congenital infection and vaccination.
Absence of cell-mediated immunity to rubella virus 5 years after rubella
vaccination
Challenge with rubella virus after loss of detectable vaccine-induced
antibody
Failed rubella immunization in adults: association with immunologic and
virological abnormalities.
In vitro correlates of cell-mediated immunity in human tonsils after
natural or induced Rubella virus infection.
Rubella antibody titers in vaccinated and nonvaccinated women and results
of vaccination during pregnancy.
Subclinical rubella reinfection during pregnancy followed by transmission
of virus to the fetus.
Congenital rubella after successful vaccination
Persistence of vaccine-induced immune responses to rubella: comparison with
natural infection.
Other
Rubella vaccine and susceptible hospital employees. Poor physician
participation.

The following are ‘allowable’ reactions that ‘they’ will ‘allow’ as
reactions to this vaccine

http://www.vaers.org/reportable.htm
Table of Reportable Events
Following Vaccination (RET)

http://www.ncbi.nlm.nih.gov/books/bv.fc ... table.8477