The closer the remedy is to the "simillimum" the more devastating the
effects of an aggravation will be.
Since we are prescribing (hopefully

a wholly different situation than a proving -with notable exception of those
provers who have at times been force to withdraw from a proving...
who must be assumed to have been too susceptible to the remedy through one
of two dimensions:
Either the remedy was for them a somewhat "near simillimum"
Or they were simply highly sensitive in general at that time, either as an
overall personal characteristic, or because of some particular state of
dis-ease existing at that moment.
Since the Organon explains in perfect logic why one should not use more than
the amount of medicine needed to do the job (in case we are sadly lacking
in common sense

our adjustments to the amount when/if needed.
best regards,
Dave Hartley
www.Mr-Notebook.com
http://www.localcomputermart.com/dave
Santa Cruz, CA (831)423-4284