LYMPHOBLASTIC LEUKAEMIA
Posted: Thu Nov 24, 2005 7:01 pm
Hello Fellow Doctors,
I would like to have an opinion in a case of B-precursor lymphoblastic
lukaemia in a young child of 7yrs of age. The child was born with 3.75 kgs
of birthweight. The child has been very much social as her mother states.
When she was borught to me she was under the effect of oral Morphine
continuously for relief from the pain for severe headache. Her hemapathology
report is as follows:
R.B.C : Mild hypochromia with anisocytosis. Polychromasia+ Normoblasts seen.
W.B.C: Leucocytosis with 88 percent blasts seen. 2 types of blasts+
Platelets: Count reduced.
Bone Marrow Aspiration study shows hypercellular marrow with 63% blasts.
Mature lymphocytes seen. haemopoetic elements reduced.
The patient was under chemotherapy for the last 1 and a half years. Now
within the last 2 months the patient developed severe headache and for this
she is under morphine continuously. The patient vomits often. Has h/o
epilepsy when the child was born. She was given phenobarbitone for the same
for 3 months . Seizures did not appear after that. The child always feels
heat even before medications. She has head sweats. There was recurrent
tendency to catch cold easily. Even though child was chubby in childhood she
started emaciating very much in 3 yrs of age. There is recurrent infection
of dorsum of feet with vescicular eruptions in the childhood treated with
allopathy. Child prefers cold drinks. Her milestones were regular.
The present conditon is that when C.S.F was examined cellular smears show dense collection of blasts with large and small forms having intended nuclei along with occassional lymphocytes.I would like the opinion of my fellow doctors regarding therapeutics as well as accessory management in the above case.
[Non-text portions of this message have been removed]
I would like to have an opinion in a case of B-precursor lymphoblastic
lukaemia in a young child of 7yrs of age. The child was born with 3.75 kgs
of birthweight. The child has been very much social as her mother states.
When she was borught to me she was under the effect of oral Morphine
continuously for relief from the pain for severe headache. Her hemapathology
report is as follows:
R.B.C : Mild hypochromia with anisocytosis. Polychromasia+ Normoblasts seen.
W.B.C: Leucocytosis with 88 percent blasts seen. 2 types of blasts+
Platelets: Count reduced.
Bone Marrow Aspiration study shows hypercellular marrow with 63% blasts.
Mature lymphocytes seen. haemopoetic elements reduced.
The patient was under chemotherapy for the last 1 and a half years. Now
within the last 2 months the patient developed severe headache and for this
she is under morphine continuously. The patient vomits often. Has h/o
epilepsy when the child was born. She was given phenobarbitone for the same
for 3 months . Seizures did not appear after that. The child always feels
heat even before medications. She has head sweats. There was recurrent
tendency to catch cold easily. Even though child was chubby in childhood she
started emaciating very much in 3 yrs of age. There is recurrent infection
of dorsum of feet with vescicular eruptions in the childhood treated with
allopathy. Child prefers cold drinks. Her milestones were regular.
The present conditon is that when C.S.F was examined cellular smears show dense collection of blasts with large and small forms having intended nuclei along with occassional lymphocytes.I would like the opinion of my fellow doctors regarding therapeutics as well as accessory management in the above case.
[Non-text portions of this message have been removed]