Hahnemann's Organon of Medicine
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Aphorism 130:
'If, at the very commencement, the first dose
administered shall have been sufficiently strong, this
advantage is gained, that the experimenter learns the
order of succession of the symptoms and can note down
accurately the period at which each occurs, which is
very useful in leading to a knowledge of the genius of
the medicine, for then the order of the primary
actions, as also that of the alternating actions, is
observed in the most unambiguous manner. A very
moderate dose, even, often suffices for the
experiment, provided only the experimenter is endowed
with sufficiently delicate sensitiveness, and is very
attentive to his sensations. The duration of the
action of a drug can only be ascertained by a
comparison of several experiments.'
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Hahnemann's Organon of Medicine - Aphorism 130
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