Coeliac disease and related conditions
Posted: Wed Jan 08, 2014 6:35 pm
From: Pulse Extra [mailto:extra@pulsetoday.co.uk]
Sent: 07 January 2014 12:31
To: finrod@finrod.co.uk
Subject: Coeliac disease and related conditions
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Dear Colleague
7 January 2014
Coeliac disease is caused by a heightened immunological response to gluten in genetically susceptible people. Once triggered, the disease process can only be treated by eliminating gluten from the diet for life.1
Historically, coeliac disease was believed to be uncommon; however, population-based studies have now revealed that it occurs more often than previously thought. In the UK, the prevalence of coeliac disease ranges between 0.8% and 1.9% - although only 10-15% are diagnosed.2
The prevalence of coeliac disease is considered to be greater in people with autoimmune conditions, such as type 1 diabetes or autoimmune thyroid disease, and in first-degree relatives of people with coeliac disease.
•
Type 1 diabetes - approximately 2-4% are affected by coeliac disease
•
Autoimmune thyroid disease - approximately 2-4% are affected by coeliac disease.
•
First degree relatives - 5-19% incidence
•
Increased incidence in patients with Down's syndrome
•
Selective IgA deficiency - approximately 10% are affected by coeliac disease3
Coeliac disease is traditionally associated with gastrointestinal symptoms (such as diarrhoea, abdominal pain, bloating, constipation and indigestion), because chronic inflammation of the small intestine is a feature of the immune response to gluten.2
In fact, symptoms for coeliac disease may be similar to irritable bowel syndrome (IBS) and consequently misdiagnosis with IBS may occur.1
However, non-gastrointestinal features of coeliac disease are increasingly being recognised in people presenting with the disease.
Delayed diagnosis is a concern as it means the symptoms of coeliac disease remain untreated and because of the possible long-term effects of undiagnosed coeliac disease.2
Small bowel cancer and osteoporosis, for example, are complications of undiagnosed coeliac disease. Once on a gluten-free diet, the patient's risk of malignancy is reduced to that of the general population. However, the increased risk of osteoporosis in the coeliac population persists due to less effective absorption.1
References
1. Pulse. Ten top tips - coeliac disease.
2. NICE. Coeliac disease Recognition and assessment of coeliac disease (CG86) , May 2009.
3. GPNotebook. GPNotebook. Coeliac disease - high risk groups
More from stories from Pulse
Pulse Learning. Challenges in gastroenterology.
Sponsor's information
thinkCOELIAC.co.uk is a comprehensive educational resource for the identification and management of coeliac disease. The site, supported by a library of videos from experts in coeliac disease, covers three main areas:
think COELIAC!
This section includes:
•
A detailed background to coeliac disease, supported by a presentation from Dr John O'Malley
•
Information on the pathophysiology of coeliac disease
•
A detailed list of symptoms and complications of not treating coeliac disease
•
An interactive list of comorbidities in which coeliac disease is more prevalent including:
* IBS, supported by presentations from Dr Shahzadi Saleem and Dr John O'Malley
* Type 1 diabetes, supported by presentations from Dr Tia McGregor and Diabetes Nurse Specialist Rosie Walker
* Infertility and poor pregnancy outcomes, supported by a presentation from Dr Jamie Dalrymple
* Autoimmune thyroid disorders, supported by a presentation from Dr Richard Stevens
test COELIAC!
This section includes:
•
A guide to testing and diagnosing coeliac disease according to the NICE guidelines on the recognition and assessment of coeliac disease (CG86)
•
A summary of the NICE guidelines and a discussion on the benefits of diagnosing coeliac disease, supported by a presentation from Nurse Consultant Helen Griffiths
treat COELIAC!
•
Comprehensive advice on implementing a gluten free diet, supported by a presentation from Marianne Williams, Specialist Community Dietician
The website also contains a selection of downloadable, ready to use professional development meetings. The meetings have been developed to help you share knowledge in your workplace and earn CPD points. These sessions cover areas such as coeliac disease and diabetes and coeliac disease and IBS.
Click here to visit thinkCOELIAC.co.uk
Download PulseToday
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Request your copy of Pulse
Send us your feedback
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® Cogora 2013
Cogora Limited, 140 London Wall, London EC2Y 5DN, is a company registered in the United Kingdom with reg. No. 2147432 http://www.cogora.com/
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Sent: 07 January 2014 12:31
To: finrod@finrod.co.uk
Subject: Coeliac disease and related conditions
If you are still having problems viewing this message, please click here for additional help.
To ensure you receive our emails please add updates@pulse-today.co.uk to your address book.
Follow us on
Forward to a friend | New email alerts
Dear Colleague
7 January 2014
Coeliac disease is caused by a heightened immunological response to gluten in genetically susceptible people. Once triggered, the disease process can only be treated by eliminating gluten from the diet for life.1
Historically, coeliac disease was believed to be uncommon; however, population-based studies have now revealed that it occurs more often than previously thought. In the UK, the prevalence of coeliac disease ranges between 0.8% and 1.9% - although only 10-15% are diagnosed.2
The prevalence of coeliac disease is considered to be greater in people with autoimmune conditions, such as type 1 diabetes or autoimmune thyroid disease, and in first-degree relatives of people with coeliac disease.
•
Type 1 diabetes - approximately 2-4% are affected by coeliac disease
•
Autoimmune thyroid disease - approximately 2-4% are affected by coeliac disease.
•
First degree relatives - 5-19% incidence
•
Increased incidence in patients with Down's syndrome
•
Selective IgA deficiency - approximately 10% are affected by coeliac disease3
Coeliac disease is traditionally associated with gastrointestinal symptoms (such as diarrhoea, abdominal pain, bloating, constipation and indigestion), because chronic inflammation of the small intestine is a feature of the immune response to gluten.2
In fact, symptoms for coeliac disease may be similar to irritable bowel syndrome (IBS) and consequently misdiagnosis with IBS may occur.1
However, non-gastrointestinal features of coeliac disease are increasingly being recognised in people presenting with the disease.
Delayed diagnosis is a concern as it means the symptoms of coeliac disease remain untreated and because of the possible long-term effects of undiagnosed coeliac disease.2
Small bowel cancer and osteoporosis, for example, are complications of undiagnosed coeliac disease. Once on a gluten-free diet, the patient's risk of malignancy is reduced to that of the general population. However, the increased risk of osteoporosis in the coeliac population persists due to less effective absorption.1
References
1. Pulse. Ten top tips - coeliac disease.
2. NICE. Coeliac disease Recognition and assessment of coeliac disease (CG86) , May 2009.
3. GPNotebook. GPNotebook. Coeliac disease - high risk groups
More from stories from Pulse
Pulse Learning. Challenges in gastroenterology.
Sponsor's information
thinkCOELIAC.co.uk is a comprehensive educational resource for the identification and management of coeliac disease. The site, supported by a library of videos from experts in coeliac disease, covers three main areas:
think COELIAC!
This section includes:
•
A detailed background to coeliac disease, supported by a presentation from Dr John O'Malley
•
Information on the pathophysiology of coeliac disease
•
A detailed list of symptoms and complications of not treating coeliac disease
•
An interactive list of comorbidities in which coeliac disease is more prevalent including:
* IBS, supported by presentations from Dr Shahzadi Saleem and Dr John O'Malley
* Type 1 diabetes, supported by presentations from Dr Tia McGregor and Diabetes Nurse Specialist Rosie Walker
* Infertility and poor pregnancy outcomes, supported by a presentation from Dr Jamie Dalrymple
* Autoimmune thyroid disorders, supported by a presentation from Dr Richard Stevens
test COELIAC!
This section includes:
•
A guide to testing and diagnosing coeliac disease according to the NICE guidelines on the recognition and assessment of coeliac disease (CG86)
•
A summary of the NICE guidelines and a discussion on the benefits of diagnosing coeliac disease, supported by a presentation from Nurse Consultant Helen Griffiths
treat COELIAC!
•
Comprehensive advice on implementing a gluten free diet, supported by a presentation from Marianne Williams, Specialist Community Dietician
The website also contains a selection of downloadable, ready to use professional development meetings. The meetings have been developed to help you share knowledge in your workplace and earn CPD points. These sessions cover areas such as coeliac disease and diabetes and coeliac disease and IBS.
Click here to visit thinkCOELIAC.co.uk
Download PulseToday
news RSS feeds
Request your copy of Pulse
Send us your feedback
Manage your emails and email address
® Cogora 2013
Cogora Limited, 140 London Wall, London EC2Y 5DN, is a company registered in the United Kingdom with reg. No. 2147432 http://www.cogora.com/
Our emails may also include information from other carefully selected companies including promotional materials from pharmaceutical companies similar to the messages seen on the PulseToday, SearchMedica and GPnotebook websites that may be of interest to you.
In association with GPnotebook
If you wish to unsubscribe, please click on the link below.
Please note this is an automated operation.
http://pulsetoday.msgfocus.com/u/14vjOv6QxN7ATQ