ingredients in allergy shots - from another list I am on
Yes
I would find a homeopath to treat you
http://neuro-www.mgh.harvard.edu/forum/ ... nallergyex
tract.html
Albumin in allergy extract
This response submitted by Linda Zambenini , RN on 2/7/98.
Email Address:
lzambeni@indiana.edu
Ask any allergist what the "diluents" are. They are either a
combination of HSA (human serum albumin),normal saline, and phenol OR
glycerol, normal saline and phenol. The glycerol based solution is
almost always used for skin testing since it has higher viscosity and
thus tends not to "bleed" into adjacent test sites and obscure
results. From my experience working in an Immunization/Travel clinic
it seems most extracts are HSA based, not glycerol. Glycerol is not
used as often because it tends to cause more reactivity and sterile
abcesses especially at larger doses. All this info can be found in
the "Immunofacts" book which we have at our office -it is an
excellent resource book on vaccines and immunobiologicals. I can get
you the publisher and ISBN # if you want it. Also, patients who are
RAST tested for allergies (blood test) instead of skin tested have
their allergy extracts ordered from and produced by large
pharmaceutical companies who deal in immunobiologicals, rather than
having the allergist formulate them in the office. Bayer and Allermed
are a couple of the companies that come to mind. When we get these
vials of allergy extract to administer to a patient they come with
extensive package inserts (you practically need a microscope to read)
just like any other prescription drug. They all use different
formulations - some mix cat pelt allergen using the HSA mixture,
others use this for their dust mites etc... I have read this on the
ingredient list on the package inserts. HSA is used as a protein
stabilizer (as is glycerol) to extend shelf life. Without HSA or
glycerol (ie: just normal saline and phenol} the allergy extract is
only good a short time- I beleive just a few hours or days. Maybe you
could get a package insert from an allergist that employs RAST
testing, or from Bayer if you are interested. Allergy extract
formulated in the allergist's office almost never list the diluents
used - just the allergens (cat,dust, mold, ragweed, pollens,
cockroach,dog etc...).
I learned about allergy extract diluents accidently about 2 weeks ago
when I was flipping through our "Immunofacts" book looking for some
info about a vaccine. There was a single page dedicated to allergenic
diluents - I was quite surprised to learn that HSA was used. I always
thought they were formulated with saline or glycerol and phenol. I
also get allergy shots and contacted my allergist. Sure enough my
dust mites vial was diluted with the HSA diluent. I asked my
allergist to reformulate it and told him my concerns. He has agreed
to do this but made a point of saying it is FDA approved , which it
is. However, I choose to have control over what goes in my body till
more is known. I do not beleive non-essential products (like allergy
extracts) should contain HSA; till more is known these should be
reformulated , which is possible, to eliminate any risk.
http://www.greerlabs.com/47.aspx
WARNINGS
Concentrated extracts must be diluted with a sterile diluent (such as
normal saline, buffered saline, saline with human serum albumin, or
saline with 10% glycerin) prior to use in a patient for intradermal
testing. Concentrates of Allergenic Extracts are manufactured to
assure high potency and have the ability to cause serious local and
systemic reactions including death in sensitive patients. Most
reactions occur within 20 minutes after injection, but may occur
later. To minimize the potential for local or systemic reactions, the
relative sensitivity of the patient must be assessed from the
allergic history and from clinical observations. Patients should be
informed of the possibility of these reactions and the precautions
should be discussed prior to testing
http://www.wramc.amedd.army.mil/departm ... roduct.htm
1. Aqueous Extract Solutions Sterile aqueous stock solutions comprise
the vast majority of allergen extracts on the shelves of the USACAEL.
A typical aqueous extract solution as prepared by our contract
manufacturer, Bayer Laboratories, will contain the active ingredients
or allergens as noted on the label (pollen, dander, molds, dust
etc.). The preservative is 50% V/V glycerin, 0.4% phenol or in a few
instances where phenol cannot be used 0.1% thimerosal. Additional
ingredients include 0.5% sodium chloride and 0.275% sodium
bicarbonate. These solutions should be clear and free from any
particulate matter. The supplied concentration of these solutions is
usually expressed as Protein Nitrogen Units per ml (ie. 10,000 or
20,000 PNU/ml) or Weight per Volume (ie. 1:10 or 1:20 W/V)
concentrations from the manufacturer. The large part of our inventory
(attached) are stocked at PNU/ml and W/V concentrations. The FDA is
working hard to better standardize allergen extract products. The
continued utilization of these products and scientific advances have
aided in the gradual refinement of earlier allergen extract products.
The perfect allergenic extract as been defined as one that contains
all the potential allergens in their native form, in the proper ratio
and with all irrelevant material removed. Currently, however, only a
few relevant "allergens" have been isolated in only a small number of
extract products (Fel d 1 or Cat Allergen 1 in Cat extracts and
Antigen E in Short ragweed extract for example).
Diluents and Preservatives Dilutions of concentrated extracts
prepared for diagnostic testing materials and treatment sets retain
potency longer when diluted with Human Serum Albumin saline diluent
(HSA) than with plain buffered or phenol saline alone. Glycerin is a
superb stabilizer and extracts in 50% solution retain their potency
for considerable periods of time. It must be noted, however, that
when extracts containing more than 10% glycerin are injected, a
burning sensation occurs at the site of injection which is not well
tolerated by patients. Thus, intradermal testing materials (ID) are
diluted with HSA diluent rather than a 50% glycerin solution. Prick
or scratch testing materials, on the other hand, may be diluted and
stabilized with glycerin. This is due to the fact that glycerin is
not irritating on the surface of the skin. Thus, prick or scratch
testing materials are in 50% glycerin. Immunotherapy treatment sets
for patients are diluted down with HSA diluent except where Center-
Al or Allpyral extracts are being used. In instances where these alum-
precipitated extracts are being used the preferred diluent is phenol
saline diluent (0.9% sodium chloride and 0.4% phenol).
Finally found a package insert!
http://www.hollister-stier.com/download ... 07-H02.pdf
OVERDOSAGE: See ADVERSE REACTIONS Section.
DOSAGE AND ADMINISTRATION:
1. General
Sterile aqueous diluent containing albumin (human) [Albumin Saline
with Phenol (0.4%)] or diluent
of 50% glycerin may be used when preparing dilutions of the
concentrate for immunotherapy. For
intradermal testing dilutions, Albumin Saline with Phenol (0.4%) is
recommended.
Dilutions should be made accurately and aseptically, using sterile
diluent, vials, syringes, etc. Mix
thoroughly and gently by rocking or swirling.
Parenteral drug products should be inspected visually for particulate
matter and discoloration prior
to administration whenever solution and container permit.
------------------------------------------
Sheri Nakken, R.N., MA, Hahnemannian Homeopath
http://homeopathycures.wordpress.com/ &
http://vaccinationdangers.wordpress.com/
ONLINE/Email classes in Homeopathy; Vaccine Dangers; Childhood Diseases
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