Cortisone- Julian's
Posted: Fri May 04, 2007 11:36 am
CORTISONE AND CORTICOIDES
[54], [112], [165], [242],.[243], [333], [418], [453], [464], [487], [488], [521], [527], [540].
Cortisone or compound of E de Kendall, is the: 17 hydroxy- 11 dehydrocorticosterone of which the formula is written:
C21-H28-05; P.M. = 360,46; P.F.: 218 degree-220 degree
Used under the acetate form, it is at present prepared synthetically.
The cortisone is a cortico-suprarenal, belonging to the group of 11 -oxysteroides or glucido-protidic hormones.
Its fundamental properties are: augumentation of the neo-glycogenesis; diminution of the utilisation of glucides by the tissues, negativation of the balance of nitrogen, elimination of uric acid through urine, of creatinine (without modification of the creatininuria) and of potassium, retention of sodium, variable action on the urinary elimination of phosphorus and calcium, involution of lymphoid organs with lymphocytopenia, augumentation of V globulines of plasma, inhibition of reactions of inflammation of conjunctivas.
Moreover, inhibits the production of A.C.T.H. and produces of cortico-suprarenal cortex.
Gives an impression of well-being and euphoria.
But there is the possibility of depressive psychic mania.
The corticoides are a group of synthetic bodies of similar activity analogous to that of cortisone, but is more powerful in the same weights of theoretically better tolerance.
In fact, all cortisones may cause some troubles as for example: perforation of gastro-duodenal ulcer, gastro-duodenal hemorrhages, psychic troubles, hirsuitism, acne, osteoporosis. diminution of resistance to infections and to tuberculosis, amenorrhoea and cushingoid syndrome.
The prodnisone and the prednisolone will cause less retention of water, of salt and less hypo-kalimia than the cortisone, but on the contrary be one of the causes of myopathies.
Among the corticoids are distinguished:
Hydrocortisone, 17-hydroxycorticosterone (Hydrocortancyl (R).
Predenisone a derivative of cortisone by deshydrogenation in position 1 and 2 (Cortancyl (R).
The Prednisolone (Hydrocortancyl (R).
Dexamethasone, fluoro 9-trihydroxy-11. Beta Methyl Prednisone, 16 beta methyl delta-l-cortisone (Betalone, Betnesor (R).
Methylprednisone (Medrol (R).
Triamcinolone, fluoro-9 and hydroxy-16 and delta 1-dehydrohydrocortisone.
The pathogenesis according to the method of Hahnemman was realised in May-June 1956 by W.L. Templeton on 8 experimentators and 5 witnesses with the dynamisations: 6 CH, 12 CH, and 30 CH. Prepared by Nelson from the substance supplied by Organon Ltd.
Allergosic (psoric) persons, slow and irritable with a heavy psychism.
Suits specially but not exclusively to carbonics, to fat sulphurs of H. Bernard.
Fat persons with the face like the full moon. sad mood, weeping without reason.
Euphoria, jolly mood.
Alternate excitation with increased activity then a state of fatigue and lassitude.
Heavy, confussed. irritable, impatient.
Want of action for calming down his irritation.
Weak memory, intellectual effort painful aggravating the general condition.
Difficult to concentrate.
Thoughts of death, melancholic state.
Headache as if from a band.
Tearing sensation, fronto-occipital.
More important pain on the right eye and on the forehead.
Pain is aggravation. by pressure, heat, movement, sun.
Better in the open air.
Throbbing headache on the right eye, in the vertex and in the left occiput.
Vertigo aggravation.
In a hot room.
Light sleep, easily perturbed, not reposing.
Restless, cannot fall asleep, wakes up fatigued.
ROUND FACE SWOLLEN FULL MOON. LEGS OEDEMATOUS SWOLLEN. DRYNESS OF THE SKIN AND MUCUS. Psychomotor slowness with irritability.
Changing mood.
"Canine" hunger, Polydypsia.
Dryness of the mouth specially in the morning.
Dryness of the throat of the pharynx, worse when swallowing the saliva, better by hot honey.
Red colour of the uvula.
Insatiable hunger.
Sees blue if he does not eat.
The milk and the fat cause nausea.
Better by empty swallowing; aggravation.
In the morning and by hot drinks.
Morning diarrhoea, while waking up, after the breakfast, after meals.
Constipation and incomplete evacuation of hard stools and in bits.
Dyspnoea aggravation.
In a hot room.
Retrosternal heaviness, difficult respiration.
Loses breath by innervatiion, being hot, in a hot room.
Laryngial cough with sneezing in the morning. aggravation. of cough by laughing, by innervation, while walking, by physical fatigue, while undressing, and shaving.
Grey expectoration, gelatinous.
Sneezing in the morning, better by washing.
Buzzing.
Ringing.
Tension behind the eyeballs.
Eyeballs painful, dry, the borders of the lids stuck together.
Styes, inflammation of the internal canthus.
Mist before the eyes.
Difficulty of accommodation.
Nycturia.
Oliguria.
Frequent micturition, shout hurry up.
DIMINUTION OF SEXUAL DESIRE. Woman: Amenorrhoea in young girls.
Heaviness of the lower-belly.
Sensation of "fullness" of the lower-belly, better by menses and walk.
Abundant menstruation, thick blood.
Dorsal pain, under the left ribs, irradiating to the sacro-illeac region (behind), better by movement, by pressure, aggravation.
In sitting position, by bending, in the morning.
Dorsal pain as if bruised.
Intra-osseous pain.
Fidgety legs, movements on the bed do not ameliorate.
Pain in the renal region, worse in sitting or lying position.
Sacro-illeac pain, as if the part is going to be bruised.
Drawing pains behind the knees.
Red streaks on the skin.
Acne of the face, shoulders, back.
In normal places growth of hairs.
Dryness and irritation of the back of hands.
Face and hands are rough, rashes in places, worse by the heat.
Round patches, slightly indurated, on the hands, and on the ankles.
Itching rash of legs of feet, of hands.
Red rash on the lower part of the sternum, on the roots of the nails, on the back of the fingers.
Dorsal face of the hands are fissured, cracked, with some red patches.
Vesicular eruption of the dorsal face of the hands, pruriginous in round patches and worse in heat.
Discoloured skin of the thorax.
Striated skin with vergeture.
Retention of chloride and sodium.
Diminution of acrobic acid.
Loss of potassium, calcium, phosphorus.
Augumentation of the creatinine, of cholesterol, or uric acid.
Glycosuria.
Augumentation of 17-cetosteroides and diminution of 17-cetosteroides.
Proteinuria.
Tubular cylinders.
Stimulation of thrombocytes, erythroid hyperplasia, leucocytary, polymorphism.
In the morning; by pressure, by an intellectual effort.
In a hot room, by fatty foods and by noise, by hot drinks.
By movement, by laughing.
While getting up, in open air.
By the menses, empty swallowing, by walk.
Right, non-exclusive.
From 5 CH to 30 CH.
Person with hydro-lipopexy.
Unstable psychism, alternating with euphoria a melancholy, from excitation to abouli.
Fronto-orbitary pain on the right side, aggravation. by the heat of a room, by pressure and afternoon.
Dryness of the mucuses of the rhino-pharynx with cough, eyes dry and stuck.
Sacro-illiac pain as if the back is going to break.
Discoloured skin, vesicular eruptions, dryness and fissure of the skin, of the face, hands with disquamation at the roots of the nails.
Impatient, quarrelsome, great ideas, burning pains and eruptions.
Sad, periodical migraine, anxious, crusty eruptions, oozing, weakness of the back and of the limbs as if dislocated.
Changing, variable, weeps for nothing, alternate smiling and tears.
Erratic pains, dry cough, venous congestion.
Allergic states.
Diabetes.
Cushing's syndrome.
Decreased resistivity to infections.
Early senescence.
Depressive, melancholic states.
Addison's disease.
Opthalmic migraine.
Sunstroke, heatstroke.
Dysthyroidia towards hypo.
(Julian)
Hepatic insufficiency.
(Gilbert and Carnot) Spasmodic entero-colitis.
Bronchitis with expectoration.
Respiratory allergy.
Allergic rhinitis (hay fever).
Allergic conjunctivitis, styes.
Nephrotic syndrome.
Oedema.
Amenorrhoea of young girls.
Pelrie congestion, eczema of vulva.
Arthralgias; osteoporosis.
Post-traumatic painful osteoporosis of Lieriche.
Acne.
Cuperosa.
Eczema with swelling of the face.
Rhagades.
Difficult cicatrisation of wounds.
Alopecia in patches.
Lupus erythematous.
Psoriasis.
It is the question of the group of synthetic substances having activity analogous to that of cortisone.
(See above) It may be noted that:
Medrol (6 methylprednisolone) causes above all an aggravation of diabetes and causes more easily gastro-duodenal ulcer.
Decadron (or dexamethasone) induces more easily necrosis of bones and osteoporosis.
Triamcionolone cause sometimes tendinous are-flexia and an amyotrophia of the quadriceps of the lower limbs.
Increased appetite and increase of weight.
Diabetes.
Aggravated infections.
Malignant varicella, influenza, zona.
Acute pancreatites
Stimulation of the mind.
Intracranial hypertension.
Headache, vomiting, bradycardia, torpour, weak sight, vertigo and convulsions: there is a papillary oedema at the base of eye.
Full moon face, hissutism, inhibition of the secretion of A.C.T.H. Goitre.
Gastric ulcer.
Arterial hypertension.
Purpura. ecchymosis.
Cataract.
Osteoporosis.
Osteonecrosis of the hips particularly.
Amiotrophia of the quadriceps of the lower limbs.
Retention of sodium.
Loss of potassium.
5 CH, 30 CH.
General anergia (diminution of the organic) capacity of reaction.
Hydrolipopexia.
Intracranial hypertension.
Pituitary, suprarenal pancreas.
Cortico-gastric dystythmia. may end in gastric ulcer.
Cataract.
Osteonecrosis of the hips.
See monography.
See monography.
See the monography on cortisone and corticotrophine as well as the positive diagnosis which summarises the clinical indications.
Registered Homeopath
EFT(Advanced) Practitioner
www.southporthomeopathy.co.uk
[54], [112], [165], [242],.[243], [333], [418], [453], [464], [487], [488], [521], [527], [540].
Cortisone or compound of E de Kendall, is the: 17 hydroxy- 11 dehydrocorticosterone of which the formula is written:
C21-H28-05; P.M. = 360,46; P.F.: 218 degree-220 degree
Used under the acetate form, it is at present prepared synthetically.
The cortisone is a cortico-suprarenal, belonging to the group of 11 -oxysteroides or glucido-protidic hormones.
Its fundamental properties are: augumentation of the neo-glycogenesis; diminution of the utilisation of glucides by the tissues, negativation of the balance of nitrogen, elimination of uric acid through urine, of creatinine (without modification of the creatininuria) and of potassium, retention of sodium, variable action on the urinary elimination of phosphorus and calcium, involution of lymphoid organs with lymphocytopenia, augumentation of V globulines of plasma, inhibition of reactions of inflammation of conjunctivas.
Moreover, inhibits the production of A.C.T.H. and produces of cortico-suprarenal cortex.
Gives an impression of well-being and euphoria.
But there is the possibility of depressive psychic mania.
The corticoides are a group of synthetic bodies of similar activity analogous to that of cortisone, but is more powerful in the same weights of theoretically better tolerance.
In fact, all cortisones may cause some troubles as for example: perforation of gastro-duodenal ulcer, gastro-duodenal hemorrhages, psychic troubles, hirsuitism, acne, osteoporosis. diminution of resistance to infections and to tuberculosis, amenorrhoea and cushingoid syndrome.
The prodnisone and the prednisolone will cause less retention of water, of salt and less hypo-kalimia than the cortisone, but on the contrary be one of the causes of myopathies.
Among the corticoids are distinguished:
Hydrocortisone, 17-hydroxycorticosterone (Hydrocortancyl (R).
Predenisone a derivative of cortisone by deshydrogenation in position 1 and 2 (Cortancyl (R).
The Prednisolone (Hydrocortancyl (R).
Dexamethasone, fluoro 9-trihydroxy-11. Beta Methyl Prednisone, 16 beta methyl delta-l-cortisone (Betalone, Betnesor (R).
Methylprednisone (Medrol (R).
Triamcinolone, fluoro-9 and hydroxy-16 and delta 1-dehydrohydrocortisone.
The pathogenesis according to the method of Hahnemman was realised in May-June 1956 by W.L. Templeton on 8 experimentators and 5 witnesses with the dynamisations: 6 CH, 12 CH, and 30 CH. Prepared by Nelson from the substance supplied by Organon Ltd.
Allergosic (psoric) persons, slow and irritable with a heavy psychism.
Suits specially but not exclusively to carbonics, to fat sulphurs of H. Bernard.
Fat persons with the face like the full moon. sad mood, weeping without reason.
Euphoria, jolly mood.
Alternate excitation with increased activity then a state of fatigue and lassitude.
Heavy, confussed. irritable, impatient.
Want of action for calming down his irritation.
Weak memory, intellectual effort painful aggravating the general condition.
Difficult to concentrate.
Thoughts of death, melancholic state.
Headache as if from a band.
Tearing sensation, fronto-occipital.
More important pain on the right eye and on the forehead.
Pain is aggravation. by pressure, heat, movement, sun.
Better in the open air.
Throbbing headache on the right eye, in the vertex and in the left occiput.
Vertigo aggravation.
In a hot room.
Light sleep, easily perturbed, not reposing.
Restless, cannot fall asleep, wakes up fatigued.
ROUND FACE SWOLLEN FULL MOON. LEGS OEDEMATOUS SWOLLEN. DRYNESS OF THE SKIN AND MUCUS. Psychomotor slowness with irritability.
Changing mood.
"Canine" hunger, Polydypsia.
Dryness of the mouth specially in the morning.
Dryness of the throat of the pharynx, worse when swallowing the saliva, better by hot honey.
Red colour of the uvula.
Insatiable hunger.
Sees blue if he does not eat.
The milk and the fat cause nausea.
Better by empty swallowing; aggravation.
In the morning and by hot drinks.
Morning diarrhoea, while waking up, after the breakfast, after meals.
Constipation and incomplete evacuation of hard stools and in bits.
Dyspnoea aggravation.
In a hot room.
Retrosternal heaviness, difficult respiration.
Loses breath by innervatiion, being hot, in a hot room.
Laryngial cough with sneezing in the morning. aggravation. of cough by laughing, by innervation, while walking, by physical fatigue, while undressing, and shaving.
Grey expectoration, gelatinous.
Sneezing in the morning, better by washing.
Buzzing.
Ringing.
Tension behind the eyeballs.
Eyeballs painful, dry, the borders of the lids stuck together.
Styes, inflammation of the internal canthus.
Mist before the eyes.
Difficulty of accommodation.
Nycturia.
Oliguria.
Frequent micturition, shout hurry up.
DIMINUTION OF SEXUAL DESIRE. Woman: Amenorrhoea in young girls.
Heaviness of the lower-belly.
Sensation of "fullness" of the lower-belly, better by menses and walk.
Abundant menstruation, thick blood.
Dorsal pain, under the left ribs, irradiating to the sacro-illeac region (behind), better by movement, by pressure, aggravation.
In sitting position, by bending, in the morning.
Dorsal pain as if bruised.
Intra-osseous pain.
Fidgety legs, movements on the bed do not ameliorate.
Pain in the renal region, worse in sitting or lying position.
Sacro-illeac pain, as if the part is going to be bruised.
Drawing pains behind the knees.
Red streaks on the skin.
Acne of the face, shoulders, back.
In normal places growth of hairs.
Dryness and irritation of the back of hands.
Face and hands are rough, rashes in places, worse by the heat.
Round patches, slightly indurated, on the hands, and on the ankles.
Itching rash of legs of feet, of hands.
Red rash on the lower part of the sternum, on the roots of the nails, on the back of the fingers.
Dorsal face of the hands are fissured, cracked, with some red patches.
Vesicular eruption of the dorsal face of the hands, pruriginous in round patches and worse in heat.
Discoloured skin of the thorax.
Striated skin with vergeture.
Retention of chloride and sodium.
Diminution of acrobic acid.
Loss of potassium, calcium, phosphorus.
Augumentation of the creatinine, of cholesterol, or uric acid.
Glycosuria.
Augumentation of 17-cetosteroides and diminution of 17-cetosteroides.
Proteinuria.
Tubular cylinders.
Stimulation of thrombocytes, erythroid hyperplasia, leucocytary, polymorphism.
In the morning; by pressure, by an intellectual effort.
In a hot room, by fatty foods and by noise, by hot drinks.
By movement, by laughing.
While getting up, in open air.
By the menses, empty swallowing, by walk.
Right, non-exclusive.
From 5 CH to 30 CH.
Person with hydro-lipopexy.
Unstable psychism, alternating with euphoria a melancholy, from excitation to abouli.
Fronto-orbitary pain on the right side, aggravation. by the heat of a room, by pressure and afternoon.
Dryness of the mucuses of the rhino-pharynx with cough, eyes dry and stuck.
Sacro-illiac pain as if the back is going to break.
Discoloured skin, vesicular eruptions, dryness and fissure of the skin, of the face, hands with disquamation at the roots of the nails.
Impatient, quarrelsome, great ideas, burning pains and eruptions.
Sad, periodical migraine, anxious, crusty eruptions, oozing, weakness of the back and of the limbs as if dislocated.
Changing, variable, weeps for nothing, alternate smiling and tears.
Erratic pains, dry cough, venous congestion.
Allergic states.
Diabetes.
Cushing's syndrome.
Decreased resistivity to infections.
Early senescence.
Depressive, melancholic states.
Addison's disease.
Opthalmic migraine.
Sunstroke, heatstroke.
Dysthyroidia towards hypo.
(Julian)
Hepatic insufficiency.
(Gilbert and Carnot) Spasmodic entero-colitis.
Bronchitis with expectoration.
Respiratory allergy.
Allergic rhinitis (hay fever).
Allergic conjunctivitis, styes.
Nephrotic syndrome.
Oedema.
Amenorrhoea of young girls.
Pelrie congestion, eczema of vulva.
Arthralgias; osteoporosis.
Post-traumatic painful osteoporosis of Lieriche.
Acne.
Cuperosa.
Eczema with swelling of the face.
Rhagades.
Difficult cicatrisation of wounds.
Alopecia in patches.
Lupus erythematous.
Psoriasis.
It is the question of the group of synthetic substances having activity analogous to that of cortisone.
(See above) It may be noted that:
Medrol (6 methylprednisolone) causes above all an aggravation of diabetes and causes more easily gastro-duodenal ulcer.
Decadron (or dexamethasone) induces more easily necrosis of bones and osteoporosis.
Triamcionolone cause sometimes tendinous are-flexia and an amyotrophia of the quadriceps of the lower limbs.
Increased appetite and increase of weight.
Diabetes.
Aggravated infections.
Malignant varicella, influenza, zona.
Acute pancreatites
Stimulation of the mind.
Intracranial hypertension.
Headache, vomiting, bradycardia, torpour, weak sight, vertigo and convulsions: there is a papillary oedema at the base of eye.
Full moon face, hissutism, inhibition of the secretion of A.C.T.H. Goitre.
Gastric ulcer.
Arterial hypertension.
Purpura. ecchymosis.
Cataract.
Osteoporosis.
Osteonecrosis of the hips particularly.
Amiotrophia of the quadriceps of the lower limbs.
Retention of sodium.
Loss of potassium.
5 CH, 30 CH.
General anergia (diminution of the organic) capacity of reaction.
Hydrolipopexia.
Intracranial hypertension.
Pituitary, suprarenal pancreas.
Cortico-gastric dystythmia. may end in gastric ulcer.
Cataract.
Osteonecrosis of the hips.
See monography.
See monography.
See the monography on cortisone and corticotrophine as well as the positive diagnosis which summarises the clinical indications.
Registered Homeopath
EFT(Advanced) Practitioner
www.southporthomeopathy.co.uk