Possible homeopathy for aminopterin rat poison in pet food - LONG
Posted: Sun Mar 25, 2007 12:58 am
Hi, Irene.
Very interesting question, this.
I'd be curious about more detailed analysis of modalities and concomitants.
With Lachesis, I would expect you would see dark, black blood and purplish
coloration, both in the bullae on the skin, and in the hemorrhages. What
color was the bleeding? I might also expect to see a strong sensitivity to
to and avoidance of being touched. The pathology would be more around the
throat than in the mouth, I would also expect. Plus, Lachesis is not
necessarily a first-line remedy one would think of for kidney
failure. --although it's certainly a possibility. I was just curious about
some of the other possibilities, in the interests of having a thorough
differential diagnosis. I'm not contradicting your thoughts about Lach.
In fact, most of the more commonly indicated remedies for kidney failure
don't fit the whole picture, other than, potentially, Ars, Phos, Ser-ang,
Vip, and Kali-chlor.
Two strongly indicated remedies in kidney failure would be Apis or Apocynum,
both of which would have a lot of swelling. Apis, of course, would be worse
heat. Apoc would be thirsty with vomiting, vomiting blood, etc... but no
indication for the blood blisters or mouth ulcers. Strophanthus is another
possible consideration -- it would have twitchings, but it's not so
ulcerative or hemorrhagic.
With Ars, which is possible, there would be chilliness, thirst for small
sips.
Another possibility is Phos, of course, if the bleeding is bright red rather
than dark red. There are some interesting precedents for considering Phos,
in addition to the toxicity from poison with a hemorrhagic and digestive set
of symptoms. One case cited by T.F. Allen that was cured by Phos:
"Dassier, Journ. de Toul., 1851(S.J. , 74, 168), effects of a large amount
of rat poison, in a girl;"
Blackwood cites the symptoms of Phos after ingestion of toxic doses from rat
poison:
"This agent, found in rat-poison and in matches, is at times the cause of
death.
- The fatal dose is about one grain. The fatal period is from half an hour
to several days.
- Symptoms.-These are varied. The immediate symptoms are irritation of the
stomach, the vomiting of material that is luminous in the dark and may be
tinged with blood. The breath often has the odor of garlic. There is
prostration with diarrhoea, the stool often containing blood. After a few
days there appears a second group of symptoms, which resemble septicaemia.
The skin is yellow and dry. There are ecchymoses in various parts; the liver
is enlarged; the urine is suppressed and contains albumin; the blood is
disorganized, and there is fatty degeneration of various organs." Again I
would assume a primary differential with Lach might be the color of the
blood and the skin lesions.
Here's another Phos article, cited from Lancet, Jan 1910, of findings after
a person ingested a toxic amount of Phos from a rat poison: "PHOSPHORUS.
The Lancet, for January 15th, contained an account of a fatal case of
phosphorus poisoning in a woman, that is of interest. The poison was rat
poison containing 4 per cent. Phosphorus, and a drachm was taken, i.c. ,
nearly 21/2 grains of the poison. Abdominal pain was the first symptom,
followed by vomiting with great thirst. Then swelling of left foot appeared
due to subcutaneous haemorrhage. For an interval of two days the patient
seemed better; then the abdominal pain returned with profuse gastric and
uterine haemorrhage. At this stage she was removed to hospital, and it was
found that from the waist down wards there were a series of very large
subcutaneous haemorrhages. There was incontinence of urine and constipation.
She died shortly after admission, three and one-half days after taking the
poison. Post-mortem the great feature was the extent of the haemorrhage into
the mediastinum, retroperitoneal tissues, mesentry, etc. The fatty
degeneration of the liver characteristic of Phosphorus was most marked, but
though Phosphorus is well known at any rate to homoeopathists as a
haemorrhage drug, the extent of the bleeding here was very noteworthy and
unusual."-Homoeopathic World. "
The symptom picture from phosphorus intoxication is interestingly similar to
what you described, even though the substance involved in this recent
poisoning is not specifically Phosphorus.
In Radar 9, Synthesis, the rubric you cite, KIDNEY- Renal Failure brings up
some relatively little known remedies. But it's obviously an incomplete
rubric, since it doesn't include most of the above-cited remedies. Also you
imply that the rubric you found had more remedies??
KIDNEYS - RENAL FAILURE
am-be.mtf11 benz-ac.br1 berb.mtf11 cupr-ar.br1 fuma-ac.mtf11 germ-met.srj5
juni-c.br1 loxo-recl.bnm10 nat-ox-act.mtf11
KIDNEYS - RENAL FAILURE - acute
germ-met.srj5
The only one of the above remedies with the hemorrhagic element in the GI
tract is Loxo-recl.
I would also think seriously of Ser-ang, or possibly Vip in addition to Lach
and Phos -- and Ter!
This is Boericke's description of Ser-ang:
"SERUM ANGUILLAE (ser-ang.)
(Eel Serum)
"The serum of the eel has a toxic action on the blood, rapidly
destroying its globules. The presence of albumin and renal
elements in the urine, the haemoglobinuria, the prolonged anuria
(24 and 26 hours), together with the results of the autopsy,
plainly demonstrate its elective action on the kidneys. Secondarily,
the liver and the heart are affected, and the alterations
observed are those usually present in infectious diseases.
From all these facts it is easy to infer, a priori, the therapeutical
indications of the serum of the eel. Whenever the kidney
becomes acutely affected, either from cold or infection or intoxication,
and the attack is characterized by oliguria, anuria and
albuminuria, we will find the eel's serum eminently efficacious to
re-establish diuresis, and in rapidly arresting albuminuria.
When during the course of heart-disease, the kidney, previously
working well, should suddenly become affected and its function
inhibited; and when besides we observe cardiac irregularities
and a marked state of asystolia, we may yet expect good results
from this serum. But to determine here the choice of this
remedy is not an easy matter. While digitalis presents in its
indications, the well-known symptomatic trilogy : arterial hypertension
oliguria and oedema;
the serum of the eel seems better
adapted to cases of hypertension and oliguria, without oedema.
We should bear in mind that the elective action of the eel's
serum is on the kidney, and I believe we can well assert that if
digitalis is a cardiac, the eel's serum is a renal remedy. So far,
at least, the clinical observations published seem to confirm
this distinction. The serum of the eel has given very small results
in attacks of asystolia; but it has been very efficacious in
cardiac uremia. There, where digitalis is powerless, the serum of the eel
has put an end to the renal obstruction and produced
an abundant diuresis. But its really specific indication seems
to be for acute nephritis a frigori. (Jousset)
Subacute nephritis. Heart diseases, in cases of failure of
compensation and impending asytole. The experiments of
Dr.Jousset have amply demonstrated the rapid haematuria,
albuminuria and oliguria caused by it. In the presence of acute
nephritis with threatening uraemia we should always think of
this serum. Very efficacious in functional heart diseases.
Mitral insufficiency, asystolia with or without oedema,dyspnoea
and difficult urinary secretion.
Relationship.-Great analogy exists between eel serum and
the venom of the Vipera.
Compare also : Pelias; Lachesis.
Dose.-Attenuations are made with glycerine or distilled
water, the lower 1x to 3 in heart disease, the higher in sudden
renal attacks. "
Certainly Ter, as Joy said, has a picture very much like the major aspects
of this toxin -- kidney damage with GI hemorrhage, subcutaneous ecchymoses,
with ulcerations of the tongue. I'd definitely put this remedy into the
differential. Although it's a remedy for typhoid, I'm not sure that it is
fatal quickly enough to correspond to this whole picture.
As I said, this poisoning presents a very interesting case analysis
challenge. Thanks so much for bringing it up and sharing your observations
on the syndrome the toxin causes. The proof, of course, will be in what
helps affected animals.
Rosemary
Very interesting question, this.
I'd be curious about more detailed analysis of modalities and concomitants.
With Lachesis, I would expect you would see dark, black blood and purplish
coloration, both in the bullae on the skin, and in the hemorrhages. What
color was the bleeding? I might also expect to see a strong sensitivity to
to and avoidance of being touched. The pathology would be more around the
throat than in the mouth, I would also expect. Plus, Lachesis is not
necessarily a first-line remedy one would think of for kidney
failure. --although it's certainly a possibility. I was just curious about
some of the other possibilities, in the interests of having a thorough
differential diagnosis. I'm not contradicting your thoughts about Lach.
In fact, most of the more commonly indicated remedies for kidney failure
don't fit the whole picture, other than, potentially, Ars, Phos, Ser-ang,
Vip, and Kali-chlor.
Two strongly indicated remedies in kidney failure would be Apis or Apocynum,
both of which would have a lot of swelling. Apis, of course, would be worse
heat. Apoc would be thirsty with vomiting, vomiting blood, etc... but no
indication for the blood blisters or mouth ulcers. Strophanthus is another
possible consideration -- it would have twitchings, but it's not so
ulcerative or hemorrhagic.
With Ars, which is possible, there would be chilliness, thirst for small
sips.
Another possibility is Phos, of course, if the bleeding is bright red rather
than dark red. There are some interesting precedents for considering Phos,
in addition to the toxicity from poison with a hemorrhagic and digestive set
of symptoms. One case cited by T.F. Allen that was cured by Phos:
"Dassier, Journ. de Toul., 1851(S.J. , 74, 168), effects of a large amount
of rat poison, in a girl;"
Blackwood cites the symptoms of Phos after ingestion of toxic doses from rat
poison:
"This agent, found in rat-poison and in matches, is at times the cause of
death.
- The fatal dose is about one grain. The fatal period is from half an hour
to several days.
- Symptoms.-These are varied. The immediate symptoms are irritation of the
stomach, the vomiting of material that is luminous in the dark and may be
tinged with blood. The breath often has the odor of garlic. There is
prostration with diarrhoea, the stool often containing blood. After a few
days there appears a second group of symptoms, which resemble septicaemia.
The skin is yellow and dry. There are ecchymoses in various parts; the liver
is enlarged; the urine is suppressed and contains albumin; the blood is
disorganized, and there is fatty degeneration of various organs." Again I
would assume a primary differential with Lach might be the color of the
blood and the skin lesions.
Here's another Phos article, cited from Lancet, Jan 1910, of findings after
a person ingested a toxic amount of Phos from a rat poison: "PHOSPHORUS.
The Lancet, for January 15th, contained an account of a fatal case of
phosphorus poisoning in a woman, that is of interest. The poison was rat
poison containing 4 per cent. Phosphorus, and a drachm was taken, i.c. ,
nearly 21/2 grains of the poison. Abdominal pain was the first symptom,
followed by vomiting with great thirst. Then swelling of left foot appeared
due to subcutaneous haemorrhage. For an interval of two days the patient
seemed better; then the abdominal pain returned with profuse gastric and
uterine haemorrhage. At this stage she was removed to hospital, and it was
found that from the waist down wards there were a series of very large
subcutaneous haemorrhages. There was incontinence of urine and constipation.
She died shortly after admission, three and one-half days after taking the
poison. Post-mortem the great feature was the extent of the haemorrhage into
the mediastinum, retroperitoneal tissues, mesentry, etc. The fatty
degeneration of the liver characteristic of Phosphorus was most marked, but
though Phosphorus is well known at any rate to homoeopathists as a
haemorrhage drug, the extent of the bleeding here was very noteworthy and
unusual."-Homoeopathic World. "
The symptom picture from phosphorus intoxication is interestingly similar to
what you described, even though the substance involved in this recent
poisoning is not specifically Phosphorus.
In Radar 9, Synthesis, the rubric you cite, KIDNEY- Renal Failure brings up
some relatively little known remedies. But it's obviously an incomplete
rubric, since it doesn't include most of the above-cited remedies. Also you
imply that the rubric you found had more remedies??
KIDNEYS - RENAL FAILURE
am-be.mtf11 benz-ac.br1 berb.mtf11 cupr-ar.br1 fuma-ac.mtf11 germ-met.srj5
juni-c.br1 loxo-recl.bnm10 nat-ox-act.mtf11
KIDNEYS - RENAL FAILURE - acute
germ-met.srj5
The only one of the above remedies with the hemorrhagic element in the GI
tract is Loxo-recl.
I would also think seriously of Ser-ang, or possibly Vip in addition to Lach
and Phos -- and Ter!
This is Boericke's description of Ser-ang:
"SERUM ANGUILLAE (ser-ang.)
(Eel Serum)
"The serum of the eel has a toxic action on the blood, rapidly
destroying its globules. The presence of albumin and renal
elements in the urine, the haemoglobinuria, the prolonged anuria
(24 and 26 hours), together with the results of the autopsy,
plainly demonstrate its elective action on the kidneys. Secondarily,
the liver and the heart are affected, and the alterations
observed are those usually present in infectious diseases.
From all these facts it is easy to infer, a priori, the therapeutical
indications of the serum of the eel. Whenever the kidney
becomes acutely affected, either from cold or infection or intoxication,
and the attack is characterized by oliguria, anuria and
albuminuria, we will find the eel's serum eminently efficacious to
re-establish diuresis, and in rapidly arresting albuminuria.
When during the course of heart-disease, the kidney, previously
working well, should suddenly become affected and its function
inhibited; and when besides we observe cardiac irregularities
and a marked state of asystolia, we may yet expect good results
from this serum. But to determine here the choice of this
remedy is not an easy matter. While digitalis presents in its
indications, the well-known symptomatic trilogy : arterial hypertension
oliguria and oedema;
the serum of the eel seems better
adapted to cases of hypertension and oliguria, without oedema.
We should bear in mind that the elective action of the eel's
serum is on the kidney, and I believe we can well assert that if
digitalis is a cardiac, the eel's serum is a renal remedy. So far,
at least, the clinical observations published seem to confirm
this distinction. The serum of the eel has given very small results
in attacks of asystolia; but it has been very efficacious in
cardiac uremia. There, where digitalis is powerless, the serum of the eel
has put an end to the renal obstruction and produced
an abundant diuresis. But its really specific indication seems
to be for acute nephritis a frigori. (Jousset)
Subacute nephritis. Heart diseases, in cases of failure of
compensation and impending asytole. The experiments of
Dr.Jousset have amply demonstrated the rapid haematuria,
albuminuria and oliguria caused by it. In the presence of acute
nephritis with threatening uraemia we should always think of
this serum. Very efficacious in functional heart diseases.
Mitral insufficiency, asystolia with or without oedema,dyspnoea
and difficult urinary secretion.
Relationship.-Great analogy exists between eel serum and
the venom of the Vipera.
Compare also : Pelias; Lachesis.
Dose.-Attenuations are made with glycerine or distilled
water, the lower 1x to 3 in heart disease, the higher in sudden
renal attacks. "
Certainly Ter, as Joy said, has a picture very much like the major aspects
of this toxin -- kidney damage with GI hemorrhage, subcutaneous ecchymoses,
with ulcerations of the tongue. I'd definitely put this remedy into the
differential. Although it's a remedy for typhoid, I'm not sure that it is
fatal quickly enough to correspond to this whole picture.
As I said, this poisoning presents a very interesting case analysis
challenge. Thanks so much for bringing it up and sharing your observations
on the syndrome the toxin causes. The proof, of course, will be in what
helps affected animals.
Rosemary