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Re: MDS

Posted: Sun Jun 19, 2016 5:20 pm
by Sherill
From Wikipedia:

Paclitaxel is a drug used to treat ovarian, breast, lung, pancreatic and other cancers.[2] It and docetaxel represent the taxane family of drugs.

Re: MDS

Posted: Sun Jun 19, 2016 11:31 pm
by Dale Moss
It's a drug, so some repertories may not have it. The RefW info came from Marsh's Clinical Drug Pictures.
From Wikipedia:

Paclitaxel is a drug used to treat ovarian, breast, lung, pancreatic and other cancers .[2] It and docetaxel represent the taxane family of drugs. Paclitaxel's mechanism of action involves interference with the normal breakdown of microtubules during cell division.

Common side effects include: hair loss, muscle and joint pains, and diarrhea, among others.[2] It results in a greater risk of infections that can potentially be serious.[2] Use during pregnancy often results in problems in the infant.[2]

Paclitaxel was discovered beginning in 1962[3] as a result of a U.S. National Cancer Institute -funded screening program; being isolated from the bark of the Pacific yew, Taxus brevifolia , thus its name "taxol". Developed commercially byBristol-Myers Squibb , the generic name has changed to "paclitaxel" with atrademark becoming Taxol. Other trademarks include Abraxane . Clinicians sometimes use the abbreviation "PTX" for paclitaxel, which is discouraged because it is not a unique identifier.

Paclitaxel is on the World Health Organization's List of Essential Medicines , the most important medication needed in a basic health system .[4] Originally, there was concern over the environmental impact of its initial sourcing from the slow growing Pacific yew. Both the assignment of rights to Bristol-Myers Squibb and the product name were subject to public debate and Congressional hearings.
Peace, Dale

Re: MDS

Posted: Mon Jun 20, 2016 12:15 am
by Rochelle Marsden
Thanks of that. I have quite a few ideas on how to proceed now

Rochelle