cushing syndrome?@Irene

[Luise Kunkle]

Hi Irene,

some weeks ago I asked about a friend where Cushing syndrome was
suspected.

Well, the diagnostic is as follows now:

Bilateral hyperplasia of adrenal cortex, ACTH completely suppressed
but 24 h urine test within normal ranges.

Would youo have any ideas on these data?

(I am posting this to the list since some seemed to be interested in
the cushing question)

Regards

Luise

--
One thought to all who, free of doubt,
So definitely know what's true:
2 and 2 is 22 -
and 2 times 2 is 2:-)
==========> ICQ yinyang 96391801 <==========

[Irene de Villiers]

Luise Kunkle wrote:

Both these things imply high cortisol produced so that it suppresses
ACTH in the feedback loop - or so I would see it.
For total cotisol 24hr-urine I presume you mean.
I really do not know how to properly interpret this, but my comments:
To me it implies that there is certainly a problem with adrenals - or
there would be no hyperplasia - also you originally described clear
cortisol-caused symptoms which is also a problem in my book - so the
"normal" urine cortisol is odd looking to me.

I'd be inclined to ask "how normal" is it?
Different labs use different guidelines on what's normal - based on a
sampling of the local populatiopn. Well if that is mainly football
stars, they make a lot of cortisol just due to stress exercise and the
"normal" can go up. If a sedentary person then reads the way an
over-excercising athlete reads - that's NOT so normal is it?

There are also different lab tests used on the 24hr-UR test - and some
are not nearly as reliable or consistent as others I have found. For
example here in Spokane there are 3 labs with different tests - only one
gives reliable and consistent readings - and the other two are all over
the place. for example same sample gave a 107 reading and a 149 reading.
I saw one result reported as "20" that was actually 202. (Someone forgot
their 3rd grade artithmetic and forgot to multiply by ten? The result
was "normal" when it should have been ten times normal.)
I'm not saying this happened in your case in point - just that it is
possible to get a lab error and that a normal reading is odd to me in
conjunction with real symptoms and real hyperplasia.

Hopefully an endocrinologist can add more insight:-)

As a homeopath I'd support the system assuming serious adrenal
exhaustion and of course the cushing's symptoms and emotional aspects -
at least until/unless you can accumulate more useful diagnostic
information to use.

On my cushing's list we also see some people with "cyclic" cushings,
where the cortisol is sometimes high and sometimes not - in a cycle.
This DOES cause cushing's symptoms - due to the regular periodic
cortisol overload which does damage before it is dissipated and/or
excreted - but the readings are often "normal" at any random lab test
point. So that's perhaps another option.

Namaste,
IRene
--
Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom/D.Vet.Hom.
P.O. Box 4703 Spokane WA 99220.
www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)
"Man who say it cannot be done should not interrupt one doing it."

[Sarvadaman Oberoi]

Dear Luis,

Hypothyroid as consequence of autoimmune thyroiditis – early stages – kept euthyroid by thyroid hormones.

Hyperplasia of both adrenal cortexes. – detected much later stage.
Comparatively raised cortisol vis-à-vis ACTH would weaken thymus and thus lower functionality of immune system.
Also lowered levels of POMC which is expressed in the pituitary gland and in the arcuate nucleus of the hypothalamus, can lead to lowered levels of ACTH and Endomorphines.
Assuming that lowered levels of POMC, the precursor to both ACTH and Endomorphines is, or rather, was the root cause:

Endomorphines would be low, stress levels would go up thereby cortisol levels would tend to rise, thus depressing the already low ACTH in the feed back to near extinction.
You could look at these sarcodes in that order:

1. Hypothalamus (hypoth.)

2. Pituitaria anterior (Thyreostimuline?, pitu-a.) (Anterior Lobe of Hypophysis) (David Flores Toledo Mexico 1987 )

3. Pituitaria glandula (Pituitrinum, Entire gland Hypophysis, pituin., pitu-gl.) (P. Sankaran India1965 and 1967)

4. Pituitaria posterior (Posterior Lobe of Hypophysis, pitu., pitu-p.) (Hering United States 1935 )

5. Corticotropinum (ACTH, Adrenocorticotropic hormone, cortico.)

6. Adrenalinum (Epinephrine, C9H13NO3, adren.) (R. Hayes 1922, Dr.V. L. Getman United States 1904)
See extracts below.
Regards.
Sarvadaman Oberoi

H 485 FF Ansals Palam Vihar

Gurgaon 122017 Haryana INDIA

Mobile: +919818768349 Tele: +911244076374

Website: http://www.freewebs.com/homeopathy249/index.htm

email: manioberoi@gmail.com
________________________________

From: minutus@yahoogroups.com [mailto:minutus@yahoogroups.com] On Behalf Of Irene de Villiers
Sent: Wednesday, May 02, 2007 12:38 AM
To: minutus@yahoogroups.com
Subject: Re: [Minutus] cushing syndrome?@Irene
Luise Kunkle wrote:

Both these things imply high cortisol produced so that it suppresses
ACTH in the feedback loop - or so I would see it.
For total cotisol 24hr-urine I presume you mean.
I really do not know how to properly interpret this, but my comments:
To me it implies that there is certainly a problem with adrenals - or
there would be no hyperplasia - also you originally described clear
cortisol-caused symptoms which is also a problem in my book - so the
"normal" urine cortisol is odd looking to me.

I'd be inclined to ask "how normal" is it?
Different labs use different guidelines on what's normal - based on a
sampling of the local populatiopn. Well if that is mainly football
stars, they make a lot of cortisol just due to stress exercise and the
"normal" can go up. If a sedentary person then reads the way an
over-excercising athlete reads - that's NOT so normal is it?

There are also different lab tests used on the 24hr-UR test - and some
are not nearly as reliable or consistent as others I have found. For
example here in Spokane there are 3 labs with different tests - only one
gives reliable and consistent readings - and the other two are all over
the place. for example same sample gave a 107 reading and a 149 reading.
I saw one result reported as "20" that was actually 202. (Someone forgot
their 3rd grade artithmetic and forgot to multiply by ten? The result
was "normal" when it should have been ten times normal.)
I'm not saying this happened in your case in point - just that it is
possible to get a lab error and that a normal reading is odd to me in
conjunction with real symptoms and real hyperplasia.

Hopefully an endocrinologist can add more insight:-)

As a homeopath I'd support the system assuming serious adrenal
exhaustion and of course the cushing's symptoms and emotional aspects -
at least until/unless you can accumulate more useful diagnostic
information to use.

On my cushing's list we also see some people with "cyclic" cushings,
where the cortisol is sometimes high and sometimes not - in a cycle.
This DOES cause cushing's symptoms - due to the regular periodic
cortisol overload which does damage before it is dissipated and/or
excreted - but the readings are often "normal" at any random lab test
point. So that's perhaps another option.

EXTRACTS:

The hypothalamus controls almost all secretions of the pituitary. The posterior lobe is controlled by nerve fibers that originate in hypothalamic neurons and the anterior lobe by substances that are transported from the hypothalamus by tiny blood vessels.

The anterior pituitary produces and secretes hormones in response to releasing hormones produced by the hypothalamus. These travel to the anterior lobe by way of a special capillary system, called the hypothalamic-hypophyseal portal system. These hypothalamic signalling hormones include:

1. TRH (thyrotropin-releasing hormone)

2. CRH (corticotropin-releasing hormone)

3. DA (dopamine, "prolactin inhibiting factor"/PIF)

4. GnRH (gonadotropin-releasing hormone)

5. GHRH (growth hormone releasing hormone)
A. The tissues in the anterior lobe of the pituitary consist of extensive vascular areas interspersed among glandular cells that secrete a number of hormones. Each is individually synthesized, probably by a specific type of glandular cell. Three such types of cells exist in the anterior pituitary gland, acidophils, basophils, and chromophobes. The anterior pituitary produces and secretes:

1. The growth hormone, thought to be synthesized by certain acidophils, stimulates all the tissues in the body to grow by effecting protein formation.
2. Adrenocorticotropic hormone (ACTH) controls the secretion of steroid hormones by the adrenal cortex, which affects glucose, protein, and fat metabolism.
3. Thyrotropin (TSH) controls the rate of thyroxine synthesis by the thyroid gland, which is the principal regulator of body metabolic rate.
4. Prolactin, which regulates the formation of milk after the birth of an infant,
5. Three separate gonadotropic hormones, follicle-stimulating hormone, luteinizing hormone, and luteotropic hormone, control the growth and reproductive activity of the gonads.
6. Endorphins (Endomorphines) released alongwith ACTH by their precursor POMC, which is expressed in the pituitary gland and in the arcuate nucleus of the hypothalamus.
B. The two hormones that are produced by the posterior lobe of the pituitary are synthesized by nerve cells in the hypothalamus. They are transported by nerve fibers to nerve endings in the posterior lobe, where they are released. The hormones are antidiuretic hormone (ADH or vasopressin), which alters the permeability of the kidney tubules, permitting more water to be retained by the body; and oxytocin, which aids in the release of milk from mammary glands and causes uterine contractions.
C. The only hormone that is synthesized by the intermediate lobe of the pituitary is the melanocyte-stimulating hormone, which appears to control skin pigmentation.
The better-known neurotransmitters of the central nervous system include the catecholamines (dopamine, epinephrine, and norepinephrine), serotonin, acetylcholine, gamma-amino butyric acid (GABA), histamine, and the opioid peptides (enkephalins, endorphins, dynorphin, neoendorphin, rimorphin, and leumorphin). These substances are distributed widely in the central nervous system and, for most, also in the pituitary gland. If a particular amine or neurotransmitter is present in nerve fibers leading to the median eminence, it probably will influence pituitary gland activity via the portal system. Dopamine, serotonin, gamma-amino butyric acid, and acetylcholine are best known for such activity. These neurotransmitters play an important, but poorly understood, role in regulating pituitary function, either directly or by their action on neuropeptide-producing neurons. Understanding the pharmacology of neurotransmitters holds promise for the treatment of basic disorders of the hypothalamic-pituitary axis.
Complete Repertory, Roger van Zandvoort

Harshness, rough

pitu-a.
MASTER F. J., Perceiving Rubrics of the Mind (mtf20)
K - Kent's Repertory;

P - Phatak's Repertory;

BB - Boenninghausen's Repertory;

Ss - Schroyen's Repertory;

Syn - Synthetic Repertory;

V - Vithoulkas Repertory.

Z - Zandvoort
Housekeeping, women inapt for

Z, Syn, Ss.

Disease Condition:

Depression

Anxiety disorder

Schizophrenia

Mania

Important Drugs: Lyc., Nux-v., Pitu-a., Sil., Sulph.
MURPHY R., Homeopathic Remedy Guide (mp4)
Pituitaria glandula

Pharmacy

Pitu-gl. Pituitaria glandula. Pituitary gland. The mother tincture comes from the organ, prepared by maceration in a mixture of water and alcohol-glycerine from the posterior lobe of the pituitary gland. Historical dose: All potencies, 6c to 30c potency.

History

The posterior hypophysis represents the least important fundamental part of the pituitary gland. Its principal physiological role is fulfilled by the antidiuretic hormone which intervenes at the kidney, where it regulates in part, the tubular reabsorption of water.

The extracts of the posterior lobe of the hypophysis cause, amongst other things, uterine motor reactions, (oxytocic action) and the vaso-constrictive reactions (hypertension) when taken in heavy doses. One oxytocin has been isolated, but vasopressin is nothing more than the anti-diuretic hormone. The Homeopathic proving was established by the Hering Proving Committee in 1935 on five provers, using the potency 12x.

Homeopathic

The pituitary gland exercises a superior control over the growth and development of the sexual organs, stimulates muscular activity and overcomes uterine inertia. Uterine inertia in second stage of labor where os is fully dilated. High blood pressure, chronic nephritis, prostatitis. Ten drops after meals, (George Fuller)

Pituitary is a vaso-constrictor and parturient. It is used chiefly for its action on the uterus either to aid in childbirth or to check bleeding after delivery. Cerebral hemorrhage. It will check hemorrhage and aid absorption of clots.

The action of this remedy has a clear anti-spasmodic tendency, especially affecting the vessels in the head. Vertigo, difficult mental concentration, confusion and fullness deep in frontal region. Nocturnal anxiety. Obsession of ideas, especially the depressive and erotic. Congestive headache.

The action of the homeopathic dilutions affects especially the female gonad glands. Painful menses with disturbed cycle. Bedwetting. Cervical pains. Pigmentation disorders and loss of hair.

Clinical

Amenorrhea. Breast disorders. Colitis. Delayed growth. High blood pressure. Prostatitis. Vertigo. Vitiligo.

Constitutions

Phosphoric, flouric types, tubercular poisoning or syphilitic with obsessions or depressive complaints. Tubercular and syphilitic types benefit particularly from the action of this remedy. Planets: Moon.

Modalities

Better from fresh air. Better in the open air. Worse from the heat. Worse in a closed room. Worse at the end of the day.

Symptoms

Mind

Anxiety, aggravated at nightfall. Obsession ideas linked to the uro-genital area. Fear of impotence, fear of passing urine. Nocturnal anguish. Tormenting thoughts, especially or erotic nature of impotence.

Abdomen

Enterocolitis. Rectocolitis. Spasmodic colon infection. Inflammation of the gallbladder.

Back

Pains in the nape of the neck, spreading to the occiput and thence to the shoulders. Neck ache. Backache.

Breasts

Atrophy of breasts. Amenorrhea with breast atrophy. Breasts hypertrophy.

Chest

Growth of hair on chest.

Ears

Buzzing with no particular modalities. Earache. Deafness in the left ear.

Eyes

Mydriasis: pupils very dilated. Weeping: the patient cries involuntarily and even without noticing. Styes, especially on the left. Conjunctivitis. Blepharitis.

Female

Difficult childbirth. Menses very painful, especially the day before and the day after the start. Dysmenorrhea. Menses scanty. Uterine pains from muscular contraction. Painful uterine contractions during childbirth.

Menses late: cycle longer than 30 days. Menses with pain during the day. Amenorrhea with breast atrophy.

Head

Alopecia of the scalp, which is very dry. Pulsating, throbbing headaches, related to hypertension. Headaches, starting at the occiput and spreading towards the base, cervical column and shoulders. Headaches, aggravated by heat, confined space, at the end of the day. Congestive headache.

Heart

Feeling of heaviness in the precordial region, aggravated by the slightest movement. The patient can 'feel his heart.' Sensation of heart constriction, aggravated by the slightest exertion. Arterial hypertension with the feeling of pounding arteries in the temples and carotid arteries. Arrhythmia. Coronary arthritis. Angina pectoris. Valvular disease. Septicemia. Cardiac neurosis. Tachycardia. Hypertension.

Kidneys

Presence of albumin in the urine. Anuria. Incontinence of urine, worse in the evening. Incontinence when the patient loses a few drops. Incontinence of urine in women with fibromatous uterus: the patient loses a few drops of urine on rising. Urinary incontinence. Nephritis.

Lungs

Asthma. Asthmatic dyspnea, accompanied by intestinal and rectal spasms. Dyspnea with abundant, watery, salty-tasting sputum, sensation of constriction in the thoracic cage. Laryngitis. Tracheitis and bronchitis. Dyspnea from anguish.

Mouth

Excessive salivation. Saliva tastes salty.

Nose

Coryza.

Rectum

Diarrhea with painful intestinal spasms. Rectal tenesmus: the patient wants to pass stools, but cannot. Proctitis. Hemorrhaging recto-colitis.

Skin

Skin cold, discolored or strongly pigmented. Alternating white and dark patches. Vitiligo. Skin is swollen, edematous, itching. Eruptions of a urticaria type. Skin very dry, scaly.

Stomach

Nausea and post-prandial distention, worse after the evening meal.

Throat

Tonsillitis. Pharyngitis.

Compare

(1) Ign. - Cortical and visceral rhythm disorders, characterized by mobility instability and paradoxical, contradictory state of symptoms.

(2) Syph. - Changing moods, forgets proper nouns, obsessions, all aggravated at night.

(3) Thuja - Fixed ideas, sad, varicosities in the nostrils, skin sticky.

Sources

Boericke.

VERMEULEN F., Concordant Materia Medica (vml4)
Pituitaria glandula

Pitu-gl.

Hypophysis posterior

Characteristics

Exercises a superior control over the growth and development of the sexual organs, stimulates muscular activity and overcomes uterine inertia. Its influence over unstriped muscular fibre is marked. Cerebral haemorrhage. Will check haemorrhage and aid absorption of clots. Uterine inertia in second stage of labour where os is fully dilated. High blood pressure, chronic nephritis, prostatitis. Vertigo, difficult mental concentration, confusion and fulness deep in frontal region. Use 30th potency.
VERMEULEN F., Synoptic Materia Medica 2 (vml3)

M – Mind

G – Generals

P- Physical
Eupionum

Eupi.

Sleep

Sleepiness during menses [1; Nux-m.]. Sleeplessness during menses [1; Pitu-a.].
Bacillus morgan-Gaertner (Paterson)

Morg-g.

Generalities

Allergy, metal dermatitis [1; Pitu-a.].
Pituitaria glandula

Pitu-gl.

Signs

Glandula pituitaria. Hypophysis. Master gland.

Unpaired compound gland suspended from the base of the hypothalamus, and consisting of two major subdivisions: the neurohypophysis [posterior lobe] and the adenohypophysis [anterior lobe]. The gland was once thought to produce mucus, hence the name pituitary [pituita = phlegm].

"The pituitary is the gland of many hormones and functions. It controls growth in childhood and adolescence, sexual development and sexual metabolism. It is necessary for proper evolution of the reproductive glands. The post-pituitary regulates the water balance of the body, blood pressure, gastrointestinal tract, and influences the fatty and sugar metabolism. It also determines the pigmentation of the skin. There is more vitamin E found in the pituitary than in any other gland. A deficiency of vitamin B castrates it physiologically and psychologically. It is as important for the pituitary as is vitamin E for the testes and placenta. Normal functioning of the pituitary involves the metabolism of manganese. Manganese foods prevent pituitary strain. These include potatoes, lettuce, agar-agar, wheat germ, liver, peanuts, walnuts and almonds ... The pituitary controls the growth and form of the skeleton. The forces of Taurus-Scorpio lay the foundation of this work, Taurus bearing the celestial pattern and Scorpio [the Lords of Form] reproducing that pattern in material form ... In biblical symbology the pituitary gland is represented variously as, for instance, by Noah's Ark, by the Cherubim hovering above the left side of the Holy of Holies, by the new moon worshipped by the twelve tribes, by the laver of purification in the Temple, and by the blessed Virgin Mary." [Heline]

"Efforts to establish the planetary correspondences to the glands have not proved entirely satisfactory. Each organ containing, as it does, all other organs, results in an unsuspected diffusion of vital principles. For instance, 'the real liver,' writes Paracelsus, 'is to be found in all parts of the body,' and only its head is in that organ which science calls the liver ... The pituitary body shares a similar plethora of correspondences. Since the advent of Uranus into the solar family, this planet has enjoyed a preferential choice as the ruler of this gland. The moon was assigned thereto by the ancients, the 'Hermetic Marriage' being the union of the sun [pineal gland] and the moon [pituitary body] in the brain. Those with a flair for riddles may find it profitable to ponder the adage that the sun rules by day and the moon by night, esp. when it is intimated that the pituitary dominates the phenomenon of sleep ... Each of the glands has several aspects of its function. It is likely that the ductless glands are all septenaries and that modified forms of the activities of all the planets may be discovered in each of the glandular centres." [Hall]

Proved by P. Sankaran in the Bombay Homoeopathic Medical College on two occasions, once in 1965 and again in 1967 by two different sets of provers. The 3x and 30th potencies of the whole gland were used. Nine provers participated in all, two of them were given sac lac as controls.

PECULIARS

M Listless; difficult concentration.

"Reads one line, then rereads it, thinking it to be another line."

Aversion to motion.

G amel. Application of cold water [headache; burning pain in eyes].

But generally agg. cold.

G Thirst for large quantities of cold water at long intervals.

G agg. Evening and towards night.

G Vertigo when not moving body or head; doubly severe on motion, esp. of head.

and Sensation of vomiting, with empty stomach [which he thinks will relieve him].

and Heavy, swollen eyes.

G Fever at night. [In 3 provers]

P Headache; starting as dull and increasing to throbbing.

agg. Evening; sun.

amel. Cold; rest; closing eyes; pressure.

and Heavy, swollen eyes.

P Sinking in stomach at noon.

Preceded by nausea at 11 a.m.

c Compare with Pituitarium anteriorium:

Redness of eyes.

Stuffy nose at night.

Constipation; stool very scanty as if some stool remained behind; stool very sticky, like jelly.

Palpitation at night before sleep agg. lying on left side.

Food

Desire: Cold drinks [1].

Notes

Pituitaria anterior

Pitu-a.

Signs

Adenohypophysis. Anterior lobe of hypophysis.

Consists of cords of cells of several different types interspersed with capillaries. The secretion of somatotropins, prolactin, thyroid-stimulating hormone, gonadotropins, adrenal corticotropin is regulated by releasing and inhibiting factors elaborated by neurons in the hypothalamus.

Pathological symptoms of the anterior lobe of the hypophysis rarely occur in humans. Very occasionally, a swelling or growth may develop which can lead in young patients to giantism and in the elderly to visual disturbances and hormone deficiencies [Simmonds' disease]. These symptoms can occur in women after a complicated confinement with major loss of blood and shock. The pituitary necrosis is then caused by ischemia.

In humans, the middle lobe of the hypophysis is poorly developed. This lobe, which is closely connected to the anterior lobe, produces a hormone whose function is only known for lower vertebrates, i.e. blending with the background colour [chameleon].

In occult physiology, it is believed that the pineal gland and the hypophysis function as the two sentries at the threshold. These two sentries, which stem from ancient esoteric tradition, work closely as catalysts in the process of acquiring spiritual consciousness in the material world. It is said of the hypophysis that its duality is inherent in the duality of the human being. In the posterior lobe, hormones are produced after information has been transferred via nerve fibres [male aspect]. In the anterior lobe, this occurs by means of the blood [female aspect]. It is believed that this duality is not expressed in the pineal gland because the hypophysis has a special link with the material world, and the duality that material evokes brings about the contrast between male and female. The moderately developed middle section is compared to the golden mean, the ability to adapt to circumstances, which is the great talent of the chameleon - a characteristic which is often seen in a negative light.

The homoeopathic drug picture is based upon 5 years of clinical observations by Dr. David Flores Toledo [Mexico], who named the remedy Hypophysinum anterioris. "Hypophysinum anterioris may well become one of the great polychrests, but it needs a careful proving. Numerous cases of acne, obesity, one of sterility, headaches related to menses, asthma, haemorrhoids, breast nodules, fungal infections of the nails, recurrent tonsillitis, vitiligo, and warts have been resolved with this medicine." [Flores Toledo, Journal of the American Institute of Homeopathy, Sept. 1987]

Compare

Natrum muriaticum. Sulphur. Pulsatilla. Calcarea carbonica. Sepia. Kali phosphoricum. Calcarea sulphuricum. Kali sulphuricum.

Region

Mind. Digestion. Female organs. Mucous membranes [nose; throat].

Leading symptoms

M Ailments from disappointed love.

Aversion to everything [friends, husband, herself].

Sexual desire diminished; enjoyment absent.

Yet fear to be alone.

M Irritability BEFORE and during menses.

Desire to strike.

Screaming and crying from anger.

M DISCOURAGED; during menses.

Causeless weeping.

Dislike of oneself.

"Easily depressed and avoids her friends."

"Feels attracted to the subway rails." [Flores Toledo]

G agg. Cold.

Lack of vital heat during menses.

Susceptible to tonsillitis, sinusitis and obstruction to nose.

G Craving for sweets and chocolate.

G Thirst for large quantities.

G agg. BEFORE MENSES.

[fearfulness; irritability; sadness; headache; coryza; pallor of face; nausea; vomiting; distended abdomen; yellow leucorrhoea; pain in ovaries; pain in uterus; difficult respiration; painful swollen breasts; low backache; sleeplessness]

G Vertigo [as if intoxicated].

agg. Entering dark room [from a lighter place].

agg. Before and during menses.

agg. Lying on back; moving head; rising from stooping.

amel. Sitting.

and Perception of colours [pink, red, yellow, green].

P Perspiration on scalp at night.

P Headache [esp. in temples] before or at beginning of menses.

agg. Light; noise; sun; warm room.

and Empty feeling in stomach [without hunger].

and Photophobia.

and Nausea.

Preceded or attended by visual disturbances.

P [Moist] eruptions on [or inflammation of] earlobes from wearing ordinary earrings [no precious metals].

P BROWN SPOTS ON FACE.

P Nausea on looking at or smell of fatty food.

P Nausea amel. eating.

P CONSTIPATION. Every other day. Every two or three days.

Stool DRY, HARD, LARGE [or like sheep dung].

and Irritability.

P Anticipatory DIARRHOEA before a date or engagement.

Diarrhoea from milk and milk products.

Rubrics

Mind

Anger in morning on waking [1]; from contradiction [1]; at trifles, during ovulation [1/1]. Dreams of death of relatives [1]; of dogs [1]; frightful [1]; paralysing [1/1]; of snakes [1]; of war [1]. Hatred [1]. Learning poorly [1]. Desire to weep, but finds it difficult [1/1]; weeping at trifles [1].

Vertigo

With tendency to fall before and during menses [1/1]. With trembling [1].

Head

Falling out of head at forehead [1]. Pain, headache coming from eyes [1/1]; headache due to contact lenses [1/1]; headache coming from nose [1/1]; pain in temples at beginning of menses [2/1].

Eye

Photophobia from sunlight [1]. Redness [3].

Nose

Discharge watery [2]; watery discharge and sneezing [2; Cob-n.]. Epistaxis during sleep [1]. Obstruction in evening [1]; alternates with pain in root of nose [1/1]. Pain as if nose were extremely dry [1/1].

Face

Sensation as if face were burnt [1/1]. Pale discolouration about eyes [1; Ptel.]. Eruptions, acne before menses [1; Arist-cl.]; acne on forehead during menses [1/1]. Cold perspiration on face before or at beginning of menses [1/1].

Mouth

Mapped tongue [3; Tarax.]. Bad taste in mouth before menses [1/1].

Stomach

Diminished appetite during menses [1; Mag-c.]. Indigestion from eggs [1]. Nausea amel. eating [2]. Pain amel. after eating a little [1/1]; amel. eructations [1]; agg. rich food [1; Puls.].

Abdomen

Flatulence, all food seems to turn to gas [1]; from fruit [1]; after vegetables [1]. Pain after eating [3]; after milk [1]; before and during menses, and distension, causing to bend double [1/1]. Rumbling after eating [3]; after milk [1].

Rectum

Diarrhoea from seafood [1/1]; after milk [1]. Itching at night [1].

Bladder

Involuntary urination when rising from a seat [1].

Female

Offensive leucorrhoea like fishbrine [1]. Menses brown at onset [1/1]; clotted, coagulated during first day and last days [1; Nat-s.]; irregular [3]; protracted and clots [1/1]. Metrorrhagia between menses [1]. Pain in ovaries before menses, agg. stepping [1/1]. Sterility [3].

Larynx

Voice, hoarseness in hot weather [1/1]; hoarseness from talking [1].

Respiration

Asthmatic respiration in morning on waking [1]; after anger [1]; amel. copious expectoration [1]; sudden attacks [1]; from change of weather [1]. Difficult respiration and headache [1]; difficult respiration before menses [1; Zinc.].

Chest

Eruptions, confluent acne [1/1]. Nodules in right breast [3]; painful nodules in left breast [3/1]. Palpitation while lying on back [1]. Perspiration in axillar regions during menses [1/1].

Back

Eruptions, confluent acne [1]; acne, cervical region [1]. Pain in sacral region during menses [1]; pain in coccyx during menses [1].

Extremities

Discolouration, white, depigmentated burning spots on upper limbs, agg. sun [1/1]. Itching eruptions on upper limbs agg. summer [1/1]. Nails do not grow [1; Ant-c.]. Perspiration of hands of hands during menses [1/1]. Swelling of thighs before menses [1/1].

Sleep

Waking as from a slight noise [1].

Skin

Discolouration, itching white spots agg. menses [1/1]. Warts pedunculated, soft and small [2/1].

Generalities

Allergy, metal dermatitis [1; Morg-g.]. Flushes of heat in young girls [1/1]. After menses amel. [1; Zinc-p.]. Obesity [3]. Weakness and cold perspiration on rising [3/1].

Food

Desire: Cakes [1]; chocolate [1]; fried potatoes [1]; fruit [1]; solid food [1]; sweets [1].

Worse: Eggs [1]; fats and rich food [1]; fruit [1]; milk [1]; seafood [1]; vegetables [1].

Notes

Pituitaria posterior

Pitu-p.

Signs

Neurohypophysis. Posterior lobe of hypophysis.

Releases the neurosecretory hormones oxytocin and antidiuretic hormone. Oxytocin is produced in the hypothalamus and then transported to the neurohypophysis, where it is stored. It causes uterine contractions at term and promotes milk release during lactation. Medically used for the induction or stimulation of labour, in the treatment of postpartum haemorrhage and atony, and to relieve painful breast engorgement. In males oxytocin stimulates the secretory ducts of the testicles.

Antidiuretic hormone, or vasopressin, is also produced in the hypothalamus and then stored in the neurohypophysis. It promotes the reabsorption of water in the kidneys [= antidiuresis], raises the blood pressure and plays a role in the water balance and production of milk. It also stimulates the storage and recall of information in memory. It narrows the arteries of the abdominal organs and is therefore used to stem haemorrhage involving abdominal blood vessels. Large doses may produce cerebral or coronary arterial spasm.

Injury of the neurohypophysis gives rise to the symptomatology of diabetes insipidus. Proved by Hering Proving Committee in 1935 on 5 subjects with 12 DH.

Compare

Pulsatilla. Natrum muriaticum. Phosphorus. Sulphur. Aristolochia clematitis. Calcarea iodata. Ferrum iodatum. Hedera helix.

Region

Mind. Gastrointestinal tract. Female organs. Circulation.

PECULIARS:

M Anxiety at beginning of night.

Obsessional ideas related to urogenital sphere [fear of becoming impotent; fear of involuntary loss of urine].

G Amenorrhoea and atrophy of mammary glands.

G Angioneurotic oedema.

G amel. Open air.

P Headache; extending downward from occiput.

Throbbing and pulsating; hypertensive.

agg. Heat; closed room; late afternoon.

and Throbbing of temporal arteries and carotids.

P Copious salivation.

Saliva tastes salty.

P Constriction of rectum.

"Wishes to evacuate stool but can't."

P Involuntary loss of urine [a few drops] when rising from seat.

P Dysmenorrhoea.

Pain day before and first day of menses.

P Difficult respiration and profuse expectoration, watery, salty.

P Discolouration of skin; white patches ??? dark patches.

Skin very dry, scaly.

Rubrics

Mind

Anxiety at night [1]. Indifference to everything [2]. Weary of life [3]. Involuntary weeping [1].

Head

Pain in occiput extending down back [1].

Face

Discolouration, brown spots, chloasma during pregnancy [1/1].

Female

Sterility [1].

Skin

Moles [1].

Notes
VITHOULKAS G., Talks on Classical Homoeopathy - The Esalen Conferences 1980 - Part 1 (vh2)
Chapter 21

Amenorrhoea

Pituitaria posterior (old abbr.)

(pitu.)

Case

This is a young woman, 23 years old, 4 feet and 9 inches tall, weighing 90 pounds. When I first saw her in December 1978, she had had amenorrhoea for one and a half years.

George: So by the age 21 menses had stopped.

Response: It had started at age 18.

George: That is what I wanted to say. You will see in the history of that person either that she had one or two periods of menses and then stopped or that the menses started very late. Immediately you can see the seat of the trouble. Yes? So I am just warning you that in such cases where you see such deep troubles, the pituitary gland is involved, and you cannot expect to have a cure within a month or two or even a year. In order to bring about menses, which may pick up in some way in spite of her being 23 years old now, you have to take care of her for at least 3 years. The depth of the diagnosis is such that you cannot expect a fast cure. You will be disappointed. So that is why we have to know a little bit of orthodox medicine. The prognosis here is long, but not perhaps incurable.

Continuing: Amenorrhoea can be underlined three times. She has a tendency to gain weight. Since age 15 or 16 she lost 20 pounds on a very restrictive diet. Then she had to stay on something like 500 to 600 calories a day in order not to gain weight. She goes on hunger binges. Then she would have to starve herself afterwards. At this point she had a diet because of glucose intolerance. The sugar curve was very high and very low.

At that point I had just started using homoeopathy and I was a little afraid to use it in her case and so I put her on a diet. She got quite a bit better and I saw her again in August of 1980. At that point, her glucose tolerance curve was much better and she was feeling much worse. In August she was feeling quite mentally and physically depressed. She had anxiety about the future (underlined twice), and anxiety about health (underlined three times). She had weakness (underlined three times) and was tired from the slightest exertion. She cried easily and preferred to cry alone. She rarely feels anger. She is worse with cold - chilly.

George: This looks like a Calc. at this point.

Question: Would you explain the underlining?

Response: Amenorrhoea (3 times), tendency to gain weight (3 times), depressed (2 times), anxiety about future (2 times), anxiety about health (3 times), weakness (3 times), cries easily (2 times), chilly and worse with cold (once). She also had dizziness on waking. When I went home this weekend I had a note in my office from her. She had continued her 700 calories a day diet with 2 cups of coffee a day. This, was strong coffee, without sugar. She says that she was sticking to this, except when she goes on a binge. She craved bread and butter (underlined three times). She would eat something like 3000 calories on one evening and then starve to death for the next week.

She says that one and a half months ago she had one day of menses. I gave her a remedy a month ago. This was the first remedy in September, but she has been drinking coffee since then.

Question: Was she craving bread and butter before the remedy?

Response: Yes.

George: So on this symptomatology, which you give us now, we have to prescribe?

Response: Yes, that is the case.

George: Do you have feedback on that?

Response: Yes, she wrote to me and said that she was much more depressed. She felt that she was at the end of her rope. She had been wanting to go and see an endocrinologist and she thought that thyroid was her only hope.

Question: If she is ready to go to an endocrinologist that fast in a case with this long term prognosis, it is going to be a really difficult case.

George: There is some information lacking. What about fruits?

Response: She has no real cravings except for bread and butter.

George: Are there any aversions?

Response: No. No aversions and no cravings either.

Response: In my experience it seems that in cases like this food cravings are irrelevant. They just stuff themselves with any sort of food. It all comes out in one direction and that direction could change at any time.

Response: But if she binges just on one item, we have to take that into consideration.

George: There is one thing that I would like to warn you about in such cases: they are very dangerous and one has to be very careful not to suppress them because they can easily go into mental disturbance. VERY EASILY!

Continuing: This young woman is not depressed ordinarily. She feels that the depression is from physical sources because at times she feels very cheerful and happy.

George: With the kind of constitution she has, there is a tendency towards diabetes.

Continuing: She is a college student right now and she is doing very well. She is VERY bright.

Question: George. Is this a case where you would have to be careful in giving remedies?

George: I wouldn't worry as much about the remedies as I would worry about that diet - 500 calories.

Continuing: I think she has been malnourished for years.

George: And also coffee at that stage is a very dangerous thing. It has given her a stimulation in order to do homework and so forth. If that girl takes a remedy by the time of her examinations, you will have a mental case on your hands.

Question: Was she only 110 pounds when she was 15?

Response: I think so, yes.

George: She is a responsible person who is able to work with her mind. They feel responsible on an emotional level.

Now, what are you going to do in that case? First you see that it is a tricky case. It is a case which is not going to be easily managed. There are underlying currents in that case. You see a girl who is very soft. Therefore you would expect to have some inferiority complexes on one level or another. At the same time, she is intelligent and she is doing well in college. But she says she is taking two cups of coffee a day. Why? Because coffee stimulates her and she is ambitious. She wants to replace the lack of height with being first in school. That drive is quite strong. She wants to be like that. You are going to interfere in that case as a health professional. And you have to correct the health. That is all you are interested in. But she is not interested in that. She is interested in being first - that is of primary importance. So you have a problem which you will have to judge in how to handle it.

If you are very strict and you say that she has to eat in order to pick up weight, it is important for her to have the stamina. Take away the coffee, which will not give the extra energy for the mind to work, and she will find herself very soon gaining weight and feeling stupid.

Continuing: She followed the diet I gave her for a week and gained a pound.

George: She gained a pound. They are afraid of picking up weight to the extent that it becomes a fixed idea - an obsession. So you have to know the problem with which you are dealing here. It is a complicated one. She is going to lose her health completely and if you explain that to her she will not understand it. So you have to find a way to compromise. Anyway coffee must go out. You cannot give a homoeopathic remedy with coffee. She is making herself diseased by her approach to diet. So the diet must be corrected definitely.

Now the third point is the remedy, you are going to give, a remedy which you know is not going to act perfectly because first of all the picture is not clear. Secondly the pathology is deep. It is a malfunction of the interior. Are you going to correct that and how much? You have to find out what the parents are like and the brothers and sisters.

Response: There is no illness in the family at all. The mother is obese.

George: That gives more help. Apart from all that, now we have to find a remedy to prescribe. What are you going to use as far as symptomatology is concerned? How shall we proceed? We shall go to the repertory. We have to take a few symptoms and repertorize it as close as possible. Which symptoms shall we take for repertorization? Give me three symptoms.

Response: I would look on obesity and anxiety about the future and cries easily.

Response: I would look under the rubric "dwarfish".

I would be tempted to use something like "dwarfish amenorrhoea" and "anxiety about health".

Response: Is this anxiety about health really anxiety about her weight?

Continuing: No, I think that she is really concerned because she realizes that she has a very severe metabolic problem.

Response: I would use anxiety about future, and dwarfishness. I would look at the bread and butter issue, but I do not believe that that is as important. The whole tendency about her working and achievement orientation, I feel, should be examined.

Question: Does she have any hair on her face?

Response: No, there is plenty of hair on her head, but none on her face.

Response: I have a hard time making a case out of that.

George: You can play with it and take three and first time and see which one comes and which you do or do not like. Then take another three or four and repertorize them.

Response: Okay. I would say bread and butter, anxiety about future, and dwarfishness.

Response: What struck me, as the interviewer, was this remarkable control that this woman kept intellectually. It has been all these years that she has kept herself under this kind of control. She could go through the day having two cups of coffee, some nuts, a carrot, an apple, and that would be all that she would have for a week or two. That was every day.

George: That would go into a state of anorexia nervosa. This is VERY bad.

Response: She should be put on a very good diet.

George: If we look under amenorrhoea, there are too many remedies. Tendency to gain weight is something I keep in mind, and I would look under dwarfishness.

So I go and look at what is most underlined in the mental sphere. There are certain symptoms which are underlined such as anxiety about the future and anxiety about health. I would compare the two and find which is the remedy that pertains to this.

There are too many remedies related to weakness. So I have to compare these remedies with another symptom which is valid. Cries easily presents too many remedies again. Chilly gives too many remedies for us to pinpoint.

I am using the repertory as a tool now. So immediately I go here to desire and aversion symptom which are very strong. For the time being, I can use that and see what is running through.

(George assigns various desires and aversions to members of the group to look up).

K.: Agar., Bell., Ferr-p., Grat., Hydr., Ign., Mag-c., Merc-d., Puls.

Response: Puls. (numerous times).

George: I got down to these two remedies (indicates on the blackboard). You go now and look in the repertory: Puls. and Sulph.

So we have dwarfish in Sulph. In amenorrhoea we have all of them.

Comment: And Ferr. is under craving for bread and butter.

George: Which would be the remedies that have weakness?

Responses: Bry., Calc., Nat-c., Lach.

Question: Are you confident you can come up with the right remedy by doing this?

George: No. In this case we are not confident. We said in the beginning that it was a different case and it would not be a straightforward remedy. Therefore we need to look again and again for one more reason that it is a different case. Forget about being accurate here in the beginning. Let's try some other combinations. What else can we try?

Another way to start is with obesity, anxiety about the future, anxiety about health, weakness, cries easily, chilly. We feel that we must think that she is suppressing something, but she does not say so, so look under suppression. Finally we take the dwarfish. So we will probably come down with Calc. or Puls. also.

Group Response: And Sulph.

George: These three now have certain similar characteristics and peculiarities. Bread and butter is Puls. The question is whether she is a chilly Puls. We can judge this from the essence. Cries easily is Puls. Prefers to be alone is not underlined. Did she cry during the interview? She is an intellectual.

Response: No, she feels that crying is a weakness.

George: What else can we use here? There is not much left that we can use. So we say she is a dwarf and we give Bar-c. (Laughter) Wait, there is another surprise in this case. This is an idea we have. Because she is a dwarf and because there is amenorrhoea, that means ... Bar-c. is very intelligent?

Response: No.

George: So again Calc. is no good. It is not Puls. Why is it not Calc.?

Response: Too intellectual.

George: Okay, let us discuss Calc.

She is an intelligent person and puts on weight easily. She is ambitious. I would be afraid in that case to give Calc. Why? Because the chilliness does not have the chilliness of carb. But the person who is undernourished is bringing up some chilliness anyway.

When she goes into mental characteristics, why doesn't that go to fears at all? Calc. whose mind has broken down and has gone into a kind of mental symptomatology will not go into anxiety about health and become depressed etc. She will go to fears and anxieties. If this had said here, "fear of insanity", I would go with that because I had a strong symptom.

Desire for sweets, which appears with Calc., does not appear at all. The vertigo from high places is not apparent. There is no characteristic symptom apart from being obese. But Ferr. also is obese, so why not use that?

Because the Ferr. is obese, is cold, and desires bread and butter - very salty. So the best prescription from our point of view would be that. Now there is another point here that says "weakness from slightest exertion". That is Ferr.

But we do not have again a characteristic of Ferr., which is "working (walking) slow ameliorates". And in Ferr. there is the circumscribed pseudo ........ They are plethoric people and you see a healthy individual. That is how a Ferr. looks - a very healthy individual with red cheeks, white skin, and very little stamina and palpitations. They will get palpitations very easily and with the least exertion.

All of the remedies which have been named are to me no good. I have no complementary symptoms to back any of them.

I will tell you something now that you should not use frequently. You would use it only when you have to make an analysis like this. And you know that the trouble is one of the pituitary. The first remedy I would use is potentized pituitary extract in that case.

Response: I had a woman that I worked on constitutionally for at least a year and a half. Finally she was given Pituitary 6x and it just turned her whole life around.

George: We are allowed after that kind of analysis to prescribe like that, but please do not use this method in every case. So after you have done this kind of analysis you are justified in giving the remedy. This is after the diet has been regulated and the coffee has been removed of course. I think that she will appreciate that it is a matter of life and death.

Question: What potency?

George: I would first try a 12 potency, one every day for about 20 days. If there is no effect in those many days, I would go higher with one dose of 200. Wait for at least one month to see if there is any change in the spheres of health and anxiety, etc.

Question: Would you consider taking her off coffee and waiting? Maybe the coffee has a dramatic effect on her symptomatology. So then see what happens regarding the symptoms.

George: You can do that as well, but if you have the right remedy and you stop the coffee so that it will not kill it, you will see dramatic changes. On cutting back the coffee, you may reduce the anxiety a bit. She is trying to break down her constitution by what she is doing. She is going to bring another level of health altogether where she will have fixed ideas and become paranoid.

Comment: She is going to have to be taught the whole spectrum of health. It will take a lot of educating.

George: That is why we have to ....

Comment: It is the only chance she has.

Question: How would you assess her vital force? A 2 or 3?

George: She has a good vital force even with what she has gone through all these years.

She still has not developed a real mental case. She has a good vital condition.

Comment: I think that what he means is that your overall assessment of her total health on a scale of ten would be .... would you say that this is a sick person?

George: On a scale of ten, I would put her at five. Why? Because she says that the family is all happy. This is of great importance.

Question: I don't understand what you mean by that. Did she have three brothers who were all 6 feet tall?

Answer: Actually, she says that she has only one sister. The family is small - all of them. They are not large people. But they are not as small as she is.

Question: That is one thing that we never even talked about. Her mother is four feet five, and her father is five feet tall, then what does that have to do significantly with the pituitary of a small person?

George: It makes much less significance, definitely. The amenorrhoea still gives you the idea that there is a malfunction of the pituitary.

Comment: In a starvation like that, amenorrhoea is not uncommon.

George: Menses started late. It is a big problem. There was suppression.

Question: So before Calc. will get depressed and develop so many anxieties, they will go through a stage of fears?

George: Yes. No, not stage of fears in general, but I would expect here that instead of anxiety about health, I should have thought that if it was Calc. that her mind would have gone towards fear of insanity, associated also with the coffee.

Question: And also the lack of desire for sweets?

George: Yes. She doesn't say anything about sweets. And she is eating so little.

Comment: This is a warm climate here in Southern California, I don't think you can put too much emphasis on the chilliness.

George: It is a warm climate and she is chilly, then of course we would put more emphasis on that. Normally she would be warm because it is a warm climate. Now she is chilly. So before I would try Calc. or Ferr., and I don't like either, I would try potentized pituitary extract and I believe that there is going to be an improvement. In consequence there is going to be a remedy on another level which will appear.

[Sarvadaman Oberoi]

Dear Luise,

Some additional extracts.
Regards.
Sarvadaman Oberoi

H 485 FF Ansals Palam Vihar

Gurgaon 122017 Haryana INDIA

Mobile: +919818768349 Tele: +911244076374

Website: http://www.freewebs.com/homeopathy249/index.htm

email: manioberoi@gmail.com

________________________________

From: minutus@yahoogroups.com [mailto:minutus@yahoogroups.com] On Behalf Of Irene de Villiers
Sent: Wednesday, May 02, 2007 12:38 AM
To: minutus@yahoogroups.com
Subject: Re: [Minutus] cushing syndrome?@Irene
Luise Kunkle wrote:
ADDITIONAL EXTRACTS

Liga Medicorum Homoeopathica Internationalis (~LMHI) 1988

Hypophysinum anterioris -five medical cases (Dr. David Flores Toledo)

Grupo placebus

Pituitaria glandula

The pathogenesy of this remedy was initiated in March of 1981, and its experimentation was clinical. In the beginning it was indicated - by the following key symptoms: Reaction to current metal earrings, - galactorrhoea, menses disturbances and periodical symptoms that coincided with the menstruation.

It was administered for the first time in the case of a rebellious galactorrhoea, when first treated with allopathic medication and afterwards with homoeopathic treatment; fruitfully, I observed the disappearance of the inflammatory reaction to the current metal earrings and a correction to old menses disturbances, which had only progressed to a better stage but not cured with the remedies best selected.

With only these symptoms there commenced an indication of a remedy and I also observed the disappearance of other ailments. When the - symptoms which was disappearing was a chronic and clear one, and not a cyclical one with a history of spontaneous disappearance, note of this was indicated in the protocol of clinical experimentation. In this manner, by September of 1986, five and half years later, there were - more than 500 symptoms. Actually, seven years later, the pathogenesy - now has 766 symptoms, which is remarkable, having in mind that the first report of Sulphur didn't have more that 500 symptoms and that more than 50% of our pathogenesies do not come near this amount.

I will briefly report five clinical cases and they will demonstrate the action of this remedy which should be considered like a polychrest, - which was expected taking into account its important function in the - hormonal system of the pituitary gland.

Case no one

Woman of 27 years of age, with secondary sterility since four years; she had a spontaneous abortion of thirteen weeks, - indicating a low level of chorionic gonadotrophins. This pregnancy was accomplished with allopathic treatment, Chlomiphen Citrate, which is - used for ovulation.

She presents a hysterosalpingography indicating a bicorn uterus. - An ultrasonic study indicated small cysts on the right ovary and another a year and a half later, both ovaries were enlarged and policyst.

Based on the totality of the symptoms especially the gynecological ones and the characteristical reaction to the current metal earrings, - Hypophysinum anterioris was prescribed; five doses, one before every - meal, from one up to five globules progressively increased.

Twenty days afterwards, she returned indicating that her bad character of all of her life, anger from contradictions, had changed and that she felt very relaxed and tranquil. Her basal temperature ascended from 36.8 C to 37.2 C.

The physical symptoms, especially the gynecological ones, which are not possible to relate, but they improved progressively.

Ninety days after the treatment was initiated, she was pregnant - giving natural birth to a child of 3.500 Kg. in weight.

Case no two

Woman of 33 years of age, married and a housewife, with three pregnancies; two births and one spontaneous abortion.

She presents spring conjunctivitis since about a year, with a burning sensation in the eyes during the entire day, accompanied with intense itching and oedema on the eyelids.

The following key notes guided me to administer the medication: - reaction of the earlobes to current metal earrings, galactorrhoea, which did not disappear spontaneously after each pregnancy. Her mental state, screams and tits during her anger and very apprehensive are proper - symptoms of the pathogenesy, as well as the ocular symptoms and those related with the menses.

At the term of 10 days, the conjunctivitis had a notable improvement and before a lapse of 60 days, the patient was given a favorable medical discharge.

She was administered with a treatment of five doses of a 30 centesimal potency, taking from one up to five globules before every meal, three times a day.

Case no three

Man of 21 years of age, who comes to his appointment with the following symptoms:

Mental State: He begins anything with lot of courage then loses interest. Everything he does comes out wrong. He has difficulty in thinking and comprehending, nit there are times that he has a very - clear mind and learns rapid, he feels bad in a crowd.

Physical State: Central scotoma since about 10 years caused by toxic amblyopia. Vertigo when he is lying down, since several years - back, cannot precise how many. Sensation of having elastic fingers, - being able to pull them out. Sleeps very much. Dreams that he falls and this wakes him up. Incoherent dreams.

He was administered Hypohysinum anterioris at a 30 centesimal potency, from one up to five globules, based on the following symptoms which are accounted for in the pathogenesy: discouraged. Difficulty in thinking and comprehending. Weak memory. Vertigo while lying down. This is to say, we have the principal mental symptom and the general ones.

The surprise was that not only those symptoms are accounted for in the pathogenesy disappeared, but also the sensation of the elastic fingers disappeared and the idea of being able to pull them out, a symptom which I have never seen in any Repertory or in any Materia Medica. The central scotoma also disappeared, which he had since 10 years, and which only two medicaments are presented in the Repertory: Carboneum sulphuratum and Tabacum.

Case no four

Woman of 38 years of age, married, a public accountant. She arrived on her appointment with a pulsating headache, accompanied with nausea three of four times a week, since 12 years. The sensation of have ear obstruction and hypo-acoustic, which improves when swallowing, from which she suffers since 12 years. Brown facial stains. Intermittent yellow leucorrhoea since 10 years. Menses which begins with dark clots. Flaking between the toes. Halitosis. She has always had greasing hair. She was administered five doses of Hypophysinum anterioris at a potency of 30 centesimal, from one up to five globules, one dose before every meal.

She returned within a month with notable improvement in the headaches, having had the pain only three times in a month and without nausea. Her easy character continued the same.

The flaking between the toes showed a slight aggravation. The menses began without clots. The remaining physical symptoms also improved.

Surprisingly she showed me a surgical keloid cicatrice 12 cm. long, which passes over the fold of the elbow which caused difficulty to the hyperextension, which now shows to be soft and elastic. This problem had not been mentioned before.

Three months later, improvement of the symptoms above-mentioned, including that of the greasy hair of which she suffered all of her life and now states an improvement of a surgical cesarean keloid cicatrice, as well as other small cicatrices, one on the upper lip and another on the forehead caused by childhood traumatisms. The cesarean was before the intervention on the fold of the elbow. The cicatrices first to improve were the more recent ones, fulfilling in the way with the so-called Hering's law.

The patient continued improving up to the total cure of the headaches, normal menstrual periods and the almost disappearance of the keloid cicatrices.

Case no five

A female teacher of 48 years of age, who has ecchymosis in her pelvic limbs, easy fatigue and weakness, blurred vision, pain above the eyebrows, paroxysmal vertigos, moscae volitants and buzzing in the ears. Legs and feet oedemas.

She has aplastic anaemia which as provoked by Malathion which is used to fumigate her garden. She has received 22 blood transfusions en nine months; this means one every to weeks, approximately.

In has been seven months that she had a hysterectomy due to functional haemorrhage and to avoid aggravation of the anaemia.

Additionally to the proper symptoms of the ailment, she also shows the following:

Mental State: Irritable caused by trifle matters, screams when angry, which is worse since she began with her ailment.

Physical State: Eruption on the skin where the metal of the watch makes contact with the skin, on her neck because of the necklaces or because of some fabrics, swolleness of the earlobes caused by current metal earrings. Hypophysinum anterioris at a potency of 30 centesimals, from one up to five globules before each meal.

Twenty days afterwards she arrives for her appointment with an improvement of the symptoms of the aplastic anaemia. She still suffers from headaches but the frequency is less as well as the duration. The noise in her ears like the sound of a cricket have diminished a 50%. Other chronic symptoms have also disappeared, which I do not have to relate at the moment.

The last transfusion was given five days before the first medical appointment.

When the aplastic anaemia was diagnosed to 7.5, and within the following twenty days, after the medication was indicated, the level increased to 8.8 without a previous transfusion.

At a term of 50 days from the first medical appointment, another five doses were administered of Hypophysinum anterioris of 30 centesimal potency, this time dilutes in water dynamizating in every dose, five teaspoons, one daily.

Almost all of the symptoms related to the aplastic anaemia continue to improve, even though the haemoglobin level descended from 8.8 to 7 mg.%, she feels more tired, but she is eating well. Her bowel movements are normal.

At the hospital where she is under medical control, they did not have to give her a new transfusion, due to the fact that young cells appeared, indicating mieloblastic activity.

Four months after the treatment was initiated, she arrives for her medical appointments with less tiredness, the aplastic anaemia symptoms continue to improve, such as: blurred vision, headaches, dizziness, moscae volitants, noises in the ears. The oedemas on the legs and feet show a progressive remission and the haemoglobin level increased to 10 gr.%.

The Hypophysinum anterioris prescription was made taking into account the totality of the symptoms, and not only the reaction to the current metal earrings. Although her character has been the same all of her life, the mental state of the patient was also taken into account.

In January of 1988, it has been four months since she received her last blood transfusion. The haemoglobin level was maintained at 12 gr.%. Her general state is very satisfactory and she returned to her occupation as a teacher in a primary school. Before the homoeopathic treatment, she was diagnosed as incurable, with an unfavorable prognosis for a life span of six months. Officially, she should have die eleven months ago.

Abstract

This pathogenesy was initiated in March 1981, today we have 766 symptoms. First clinical case related is a secondary sterility since four years; she was pregnant after ninety days. Second clinical case, is a female with spring conjunctivitis, she had suffered from this since one year; was cured in sixty days. Third clinical case, a man of 21 years of age with difficult in thinking and comprehending, with a central scotoma since ten years because of toxic amblyopia, and a new symptom was reported: the sensation as if that of having elastic fingers and could pull them out. He was cure from scotoma and mental symptoms. Fourth clinical case, a woman, 38 years of age with headache pains since 12 years; she was cured from it and what was more amazing, some keloid cicatrices were almost disappearing. Last clinical case showed, a woman with aplastic anaemia caused by malathion insecticide; she had a bad prognosis, with only six months of life and was receiving blood transfusion every two weeks, and then the haemoglobin level was ascending from 3.4 gr.% to 7.5 gr.%. With the Homoeopathy the level was ascending to 8.8 gr.% and afterwards up to 12 gr.% without blood transfusions. She is an elemental school teacher and today is working again. Against official prognosis, she has survived thirteen months until January 1988. All five clinical cases were administered five doses, from one globule up to five globules before eating, three time a day, at 30 centesimal potency.

Dr Rajiv Saxena, Understanding Glands, Endocrinology: The Homoeopathic Approach. First Edition 2002. B Jain Publishers, India. Page 151
Pituitaria anterior

Endocrine disorders

1. Acromegaly.

2. Cretinism.

[Luise Kunkle]

Hi Irene,

Thank you once again.

What you say makes sense.

I talked to the endocrinologist and now it also makes sense what she
said. She strongly suggested (but without exerting pressure -
which makes her more credible to me:-) that in any case the patient
should take the methadone suppression test to exclude a "sub-clinical"
cushing. This did not make a lot of sense to me then, but it does now.

So I will not objectt to the test.

As far as adrenal exhaustion - whatever that may be - is concerned: I
suspect a congenital or early acquired general glandular insufficiency
that is slowly getting worse as she gets older. This would explain the
autoimmune thyreoditis, the adrenal hyperplasia, the operation for the
ovarian tumour in the past and also, what I had not mentioned, her
parotids swelling off an on during the last few years. Also she has
had liver signs off and on.

This insufficiency obviously has been resistant to homeopathic
treatment over the decades - well, may be I just was not good enough.
I did suggest her consulting other homeopaths, but she would not do so.

Well, she is now taking Rhus tox. I'll keep up with this until after
the test and will then try to learn what I can from your cushing
thread. If I do not come up with anything really convincing I will put
my foot down for her to see another homeopath:-)

Regards

Luise
--
One thought to all who, free of doubt,
So definitely know what's true:
2 and 2 is 22 -
and 2 times 2 is 2:-)
==========> ICQ yinyang 96391801 <==========

[Luise Kunkle]

Hi Sardavan,

That is great - it sort of parallels my thoughts about what has been
happening.

She was diagnosed - even then because of fatigue and depression - for
low ACTH when she was just 20. ACTH was supplemented, and she felt
much better. Hoewever, the doctor did not want to go on with it.

So I had the idea all along that the low ACTH has been the basic
illness, from which all others have sprung. I just did not understand
how it could be, and you are the first who has shown an possible
mechanism.

Thank you very very much.

Have you ever threated this condition? Have you found the sarcodes
helpful/curing? Have you any exprience with other homeopathic remedies
aside of the sarcodes? (If you hesitate to name them on the list, I
would greatly appreciate a pm.)

Regards

Luise
--
One thought to all who, free of doubt,
So definitely know what's true:
2 and 2 is 22 -
and 2 times 2 is 2:-)
==========> ICQ yinyang 96391801 <==========

[Jean Doherty]

Would be very interested in more thoughts on this as have had little success in avoiding replacement thyroxine in Hashimoto's or hypothyroidism.
Perhaps the use of ACTH ?potency , Thymus,Pit A or whole gland [how does one choose] as well as what is constitutionally indicated [Iris did help in one previous case ]would help. Have quite a severe case of Hashimoti's at moment Thank you, Jean.

[Sarvadaman Oberoi]

Dear Luise,

I have very often used ACTH 6C one dose daily in water for 7-10 days ( depending on severity) after abuse of steroids which rejuvenates some of the lost immunity after which the indicated constitutional works in 90 - 95 percent cases.
Regards.
Sarvadaman Oberoi

H 485 FF Ansals Palam Vihar

Gurgaon 122017 Haryana INDIA

Mobile: +919818768349 Tele: +911244076374

Website: http://www.freewebs.com/homeopathy249/index.htm

email: manioberoi@gmail.com

________________________________

From: minutus@yahoogroups.com [mailto:minutus@yahoogroups.com] On Behalf Of Luise Kunkle
Sent: Wednesday, May 02, 2007 9:18 PM
To: minutus@yahoogroups.com
Subject: RE: [Minutus] cushing syndrome?@Irene
Hi Sardavan,

That is great - it sort of parallels my thoughts about what has been
happening.

She was diagnosed - even then because of fatigue and depression - for
low ACTH when she was just 20. ACTH was supplemented, and she felt
much better. Hoewever, the doctor did not want to go on with it.

So I had the idea all along that the low ACTH has been the basic
illness, from which all others have sprung. I just did not understand
how it could be, and you are the first who has shown an possible
mechanism.

Thank you very very much.

Have you ever threated this condition? Have you found the sarcodes
helpful/curing? Have you any exprience with other homeopathic remedies
aside of the sarcodes?

[Sarvadaman Oberoi]

Dear Jean,

Hashimoto’s is an auto immune disorder the root(s) of which can well be different in different cases.

From the homeopathic viewpoint there is a need to establish the root cause(s) of auto immune disorder, ie abuse of steroids, thimeralis in vaccine- possibly crossing blood brain barrier, other vaccine immune mechanism related auto immunity issues, radiation, chemotherapy, genetic causes etc.
Once the root cause(s) are deduced or narrowed down then a suitable sarcode may be tried and if successful, the cure is completed by moving on to the constitutional treatment.
ACTH (related to anterior pituitary / POMC / endomorphines / cortisol ) has good potential for auto immune disorders related to abuse of steroids, like wise the gland / hormone(s) identified / deduced may be related to a particular type of auto immune disorder(s) which will need to be identified. Services of a trained immunologist or/ and an endocrinologist would be a great help.
Regards.
Sarvadaman Oberoi

H 485 FF Ansals Palam Vihar

Gurgaon 122017 Haryana INDIA

Mobile: +919818768349 Tele: +911244076374

Website: http://www.freewebs.com/homeopathy249/index.htm

email: manioberoi@gmail.com
From: minutus@yahoogroups.com [mailto:minutus@yahoogroups.com] On Behalf Of Jean Doherty
Sent: Thursday, May 03, 2007 5:56 AM
To: minutus@yahoogroups.com
Subject: Re: [Minutus] cushing syndrome?@Irene
Would be very interested in more thoughts on this as have had little success in avoiding replacement thyroxine in Hashimoto's or hypothyroidism.

Perhaps the use of ACTH ?potency , Thymus,Pit A or whole gland [how does one choose] as well as what is constitutionally indicated [Iris did help in one previous case ]would help. Have quite a severe case of Hashimoti's at moment Thank you, Jean.
Hi Sardavan,

That is great - it sort of parallels my thoughts about what has been
happening.

She was diagnosed - even then because of fatigue and depression - for
low ACTH when she was just 20. ACTH was supplemented, and she felt
much better. Hoewever, the doctor did not want to go on with it.

So I had the idea all along that the low ACTH has been the basic
illness, from which all others have sprung. I just did not understand
how it could be, and you are the first who has shown an possible
mechanism.

[Joy Lucas]

as coincidence goes I have 2 cases that came within 10 days of each other that are both suspected cases of cushings - totally unrelated people but that's how it goes sometimes - neither will go and have tests, very intelligent people (one a 49 yo man and the other a 35 yo woman), they have done their own research and I guess they are a bit wary of what might be found. I haven't taken the full case of one but I am strongly thinking of Cortisone LM or water dose for the 'sulphur type' male.

If I get permission I will post progress. Joy

http://www.joylucashomeopathy.com
http://www.homeopathicmateriamedica.blogspot.com
http://groups.yahoo.com/group/provings