Effect of Aspirin on 1918 flu victims....

Here you will find all the discussions from the time this group was hosted on YahooGroups and groups.io
You can browse through these topics and reply to them as needed.
It is not possible to start new topics in this forum. Please use the respective other forums most related to your topic.
Post Reply
Carol Orr
Posts: 688
Joined: Sun Sep 23, 2001 10:00 pm
Been thanked: 1 time

Effect of Aspirin on 1918 flu victims....

Post by Carol Orr »

Can someone remind me of the word used for what happened to the 1918 flu
victims who used aspirin and then explain why that happened(the filling up of
the lungs with blood because of the high fever?) We had a discussion on this a
few years ago. Cyclonic storms or some word like that. Thanks.


Soroush Ebrahimi
Moderator
Posts: 4510
Joined: Thu Feb 07, 2002 11:00 pm

Re: Effect of Aspirin on 1918 flu victims....

Post by Soroush Ebrahimi »

Dear Carol
Pls see http://cid.oxfordjournals.org/content/49/9/1405.full
And “PERFECT STORM”:

https://en.wikipedia.org/wiki/1918_flu_ ... _poisoning
Aspirin poisoning

In a 2009 paper published in the journal Clinical Infectious Diseases , Karen Starko proposed that aspirin poisoning had contributed substantially to the fatalities. She based this on the reported symptoms in those dying from the flu, as reported in the post mortem reports still available, and also the timing of the big "death spike" in October 1918 which happened right after the Surgeon General of the United States Army , and the Journal of the American Medical Association both recommended very large doses of 8.0-31.2 g of aspirin per day.[76] Starko also suggests that the wave of aspirin poisonings was due to a "perfect storm " of events: Bayer 's patent on aspirin expired, so that many companies rushed in to make a profit and greatly increased the supply; this coincided with the flu pandemic; and the symptoms of aspirin poisoning were not known at the time.[76]

As an explanation for the universally high mortality rate, this hypothesis was questioned in a letter to the journal published in April 2010 by Andrew Noymer and Daisy Carreon of the University of California, Irvine , and Niall Johnson of the Australian Commission on Safety and Quality in Health Care . They questioned this universal applicability given the high mortality rate in countries such as India, where there was little or no access to aspirin at the time.[77] They concluded that "the salicylate [aspirin] poisoning hypothesis [was] difficult to sustain as the primary explanation for the unusual virulence of the 1918–1919 influenza pandemic".[77]

But they overlooked that inexpensive aspirin had become available in India and other places after October 1918, when the Bayer patent expired. In responding, Starko pointed to anecdotal evidence of aspirin over-prescription in India and argued that even if aspirin over-prescription had not contributed to the high Indian mortality rate, it could still have been a major factor for other high rates in areas where other exacerbating factors present in India played less of a role.[78]
Soroush
From: minutus@yahoogroups.com [mailto:minutus@yahoogroups.com]
Sent: Tuesday, July 19, 2016 8:25 AM
To: minutus@yahoogroups.com
Subject: [Minutus] Effect of Aspirin on 1918 flu victims....
Can someone remind me of the word used for what happened to the 1918 flu
victims who used aspirin and then explain why that happened(the filling up of
the lungs with blood because of the high fever?) We had a discussion on this a
few years ago. Cyclonic storms or some word like that. Thanks.


pb000014
Posts: 184
Joined: Wed Apr 08, 2020 4:09 pm

Re: Effect of Aspirin on 1918 flu victims....

Post by pb000014 »

A cytokine storm
Sent from my Samsung device


Post Reply

Return to “Minutus YahooGroup Archives”